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The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.
Borbye-Lorenzen N, Zhu Z, Agerbo E, Albiñana C, Benros ME, Bian B, Børglum AD, Bulik CM, Debost JPG, Grove J, Hougaard DM, McRae AF, Mors O, Mortensen PB, Musliner KL, Nordentoft M, Petersen LV, Privé F, Sidorenko J, Skogstrand K, Werge T, Wray NR, Vilhjálmsson BJ, McGrath JJ. Borbye-Lorenzen N, et al. Cell Genom. 2023 Dec 13;3(12):100457. doi: 10.1016/j.xgen.2023.100457. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38116117 Free PMC article.
The GWASs for C3 and C4 protein concentrations identified 15 and 36 independent loci, respectively. We found no associations between neonatal C3 and C4 concentrations and mental disorders in the total sample (both sexes combined); however, post-hoc analyses found th …
The GWASs for C3 and C4 protein concentrations identified 15 and 36 independent loci, respectively. We found no associations between …
Biotransformation of Sclareol by a Fungal Endophyte of Salvia sclarea.
Diao M, Li C, Lu J, Meng L, Xie N. Diao M, et al. Chem Biodivers. 2023 Dec;20(12):e202301363. doi: 10.1002/cbdv.202301363. Epub 2023 Nov 15. Chem Biodivers. 2023. PMID: 37899305
A fungal endophyte, identified as the generally recognized as safe (GRAS) strain Aspergillus tubingensis, can produce labd-14-ene-3beta,8alpha,13beta-triol and 8alpha,13beta-dihydroxylabd-14-en-3-one from sclareol, involving hydroxylation and carbonylation at the C3 site. …
A fungal endophyte, identified as the generally recognized as safe (GRAS) strain Aspergillus tubingensis, can produce labd-14-ene-3beta,8alp …
Levels of type XVII collagen (BP180) ectodomain are elevated in circulation from patients with multiple cancer types and is prognostic for patients with metastatic colorectal cancer.
Crespo-Bravo M, Thorlacius-Ussing J, Nissen NI, Pedersen RS, Boisen MK, Liljefors M, Johansen AZ, Johansen JS, Karsdal MA, Willumsen N. Crespo-Bravo M, et al. BMC Cancer. 2023 Oct 6;23(1):949. doi: 10.1186/s12885-023-11470-5. BMC Cancer. 2023. PMID: 37803411 Free PMC article.
When evaluated by multivariate Cox regression analysis, high PRO-C17 was predictive for poor OS independent of risk factors and the tumor fibrosis biomarker PRO-C3. CONCLUSION: PRO-C17 measures the ectodomain of type XVII collagen in serum and is a promising non-invasive b …
When evaluated by multivariate Cox regression analysis, high PRO-C17 was predictive for poor OS independent of risk factors and the tumor fi …
Factor H preserves alternative complement function during ARDS, linked to improved survival.
Bain W, Tabary M, Moore SR, An X, Kitsios GD, McVerry BJ, Ray P, Ray A, Mallampalli RK, Ferreira VP, Lee JS, Nouraie SM. Bain W, et al. ERJ Open Res. 2023 Jun 26;9(3):00702-2022. doi: 10.1183/23120541.00702-2022. eCollection 2023 May. ERJ Open Res. 2023. PMID: 37377659 Free PMC article.
Relative factor H deficiency was associated with increased factor consumption, as evidenced by lower factor B and C3 levels and Ba:B and C3a:C3 ratios. Higher factor H levels associated with lower inflammatory markers. CONCLUSIONS: Relative factor H deficiency, high …
Relative factor H deficiency was associated with increased factor consumption, as evidenced by lower factor B and C3 levels and Ba:B …
Autoreactivity against Denatured Type III Collagen Is Significantly Decreased in Serum from Patients with Cancer Compared to Healthy Controls.
Jensen C, Drobinski P, Thorlacius-Ussing J, Karsdal MA, Bay-Jensen AC, Willumsen N. Jensen C, et al. Int J Mol Sci. 2023 Apr 11;24(8):7067. doi: 10.3390/ijms24087067. Int J Mol Sci. 2023. PMID: 37108227 Free PMC article.

Moreover, the association between anti-dCol3 levels and type III collagen degradation (C3M) and formation (PRO-C3) was investigated. Anti-dCol3 levels were significantly lower in patients with bladder (p = 0.0007), breast (p = 0.0002), colorectal (p < 0.0001), head and

Moreover, the association between anti-dCol3 levels and type III collagen degradation (C3M) and formation (PRO-C3) was investigated. …
Probing Colossal Carbon Rings.
Marlton SJP, Buntine JT, Watkins P, Liu C, Jacovella U, Carrascosa E, Bull JN, Bieske EJ. Marlton SJP, et al. J Phys Chem A. 2023 Feb 9;127(5):1168-1178. doi: 10.1021/acs.jpca.2c07068. Epub 2023 Jan 26. J Phys Chem A. 2023. PMID: 36703560
Generally, the observed charged photofragments correspond to low energy fragment pairs, as predicted by density functional theory calculations (CAM-B3LYP-D3(BJ)/cc-pVDZ). Using action spectroscopy it is confirmed that C14+ and C18+ photofragments from C28+ rings have cycli …
Generally, the observed charged photofragments correspond to low energy fragment pairs, as predicted by density functional theory calculatio …
Donor chimerism and immune reconstitution following haploidentical transplantation in sickle cell disease.
Chu Y, Talano JA, Baxter-Lowe LA, Verbsky JW, Morris E, Mahanti H, Ayello J, Keever-Taylor C, Johnson B, Weinberg RS, Shi Q, Moore TB, Fabricatore S, Grossman B, van de Ven C, Shenoy S, Cairo MS. Chu Y, et al. Front Immunol. 2022 Dec 9;13:1055497. doi: 10.3389/fimmu.2022.1055497. eCollection 2022. Front Immunol. 2022. PMID: 36569951 Free PMC article.
Tregs were elevated at 100-270 days post-transplant, returning to baseline levels at one year. At one year, C3 and C4 levels were above baseline and CH50 levels were near baseline. ...
Tregs were elevated at 100-270 days post-transplant, returning to baseline levels at one year. At one year, C3 and C4 levels were abo …
407 results