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Page 1
Assessment of Mycobacterium tuberculosis pantothenate kinase vulnerability through target knockdown and mechanistically diverse inhibitors.
Reddy BK, Landge S, Ravishankar S, Patil V, Shinde V, Tantry S, Kale M, Raichurkar A, Menasinakai S, Mudugal NV, Ambady A, Ghosh A, Tunduguru R, Kaur P, Singh R, Kumar N, Bharath S, Sundaram A, Bhat J, Sambandamurthy VK, Björkelid C, Jones TA, Das K, Bandodkar B, Malolanarasimhan K, Mukherjee K, Ramachandran V. Reddy BK, et al. Among authors: bjorkelid c. Antimicrob Agents Chemother. 2014 Jun;58(6):3312-26. doi: 10.1128/AAC.00140-14. Epub 2014 Mar 31. Antimicrob Agents Chemother. 2014. PMID: 24687493 Free PMC article.
DXR inhibition by potent mono- and disubstituted fosmidomycin analogues.
Jansson AM, Więckowska A, Björkelid C, Yahiaoui S, Sooriyaarachchi S, Lindh M, Bergfors T, Dharavath S, Desroses M, Suresh S, Andaloussi M, Nikhil R, Sreevalli S, Srinivasa BR, Larhed M, Jones TA, Karlén A, Mowbray SL. Jansson AM, et al. Among authors: bjorkelid c. J Med Chem. 2013 Aug 8;56(15):6190-9. doi: 10.1021/jm4006498. Epub 2013 Jul 17. J Med Chem. 2013. PMID: 23819803 Free article.
Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
Nordqvist A, Björkelid C, Andaloussi M, Jansson AM, Mowbray SL, Karlén A, Larhed M. Nordqvist A, et al. Among authors: bjorkelid c. J Org Chem. 2011 Nov 4;76(21):8986-98. doi: 10.1021/jo201715x. Epub 2011 Oct 7. J Org Chem. 2011. PMID: 21936546 Free PMC article.
Design, synthesis, and X-ray crystallographic studies of α-aryl substituted fosmidomycin analogues as inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Andaloussi M, Henriksson LM, Więckowska A, Lindh M, Björkelid C, Larsson AM, Suresh S, Iyer H, Srinivasa BR, Bergfors T, Unge T, Mowbray SL, Larhed M, Jones TA, Karlén A. Andaloussi M, et al. Among authors: bjorkelid c. J Med Chem. 2011 Jul 28;54(14):4964-76. doi: 10.1021/jm2000085. Epub 2011 Jul 1. J Med Chem. 2011. PMID: 21678907
Structural and functional studies of mycobacterial IspD enzymes.
Björkelid C, Bergfors T, Henriksson LM, Stern AL, Unge T, Mowbray SL, Jones TA. Björkelid C, et al. Acta Crystallogr D Biol Crystallogr. 2011 May;67(Pt 5):403-14. doi: 10.1107/S0907444911006160. Epub 2011 Apr 8. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21543842
Structure and function of carbonic anhydrases from Mycobacterium tuberculosis.
Suarez Covarrubias A, Larsson AM, Högbom M, Lindberg J, Bergfors T, Björkelid C, Mowbray SL, Unge T, Jones TA. Suarez Covarrubias A, et al. Among authors: bjorkelid c. J Biol Chem. 2005 May 13;280(19):18782-9. doi: 10.1074/jbc.M414348200. Epub 2005 Mar 6. J Biol Chem. 2005. PMID: 15753099 Free article.