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Acute cardiac transplant rejection: detection and grading with MR imaging with a blood pool contrast agent--experimental study in the rat.
Johansson L, Johnsson C, Penno E, Björnerud A, Ahlström H. Johansson L, et al. Radiology. 2002 Oct;225(1):97-103. doi: 10.1148/radiol.2251010698. Radiology. 2002. PMID: 12354991
On day 6, the allogeneic group had a relative SI change of 17.7% (SD, 8.7), whereas the syngeneic group had a change of -7.4% (SD, 2.6). ...CONCLUSION: Acutely rejecting heart transplants can be distinguished from nonrejecting ones in an animal model with MR imaging …
On day 6, the allogeneic group had a relative SI change of 17.7% (SD, 8.7), whereas the syngeneic group had a change of -7.4% …
Experimental application of thermosensitive paramagnetic liposomes for monitoring magnetic resonance imaging guided thermal ablation.
Frich L, Bjørnerud A, Fossheim S, Tillung T, Gladhaug I. Frich L, et al. Magn Reson Med. 2004 Dec;52(6):1302-9. doi: 10.1002/mrm.20289. Magn Reson Med. 2004. PMID: 15562487
The use of a liposomal paramagnetic agent with a T(1)-relaxivity that increases markedly at temperatures above the phase transition temperature (T(m)) of the liposomal membrane was evaluated during magnetic resonance imaging (MRI) guided hyperthermia ablation. A
The use of a liposomal paramagnetic agent with a T(1)-relaxivity that increases markedly at temperatures above the phase trans …
Intravascular contrast agent-enhanced MRI measuring contrast clearance and tumor blood volume and the effects of vascular modifiers in an experimental tumor.
Bentzen L, Vestergaard-Poulsen P, Nielsen T, Overgaard J, Bjørnerud A, Briley-Saebø K, Horsman MR, Ostergaard L. Bentzen L, et al. Int J Radiat Oncol Biol Phys. 2005 Mar 15;61(4):1208-15. doi: 10.1016/j.ijrobp.2004.12.020. Int J Radiat Oncol Biol Phys. 2005. PMID: 15752903
CONCLUSION: The study supports the use of the combined DCE-MRI and susceptibility contrast MRI assay with a blood pool agent in characterizing tumors and their response to treatment....
CONCLUSION: The study supports the use of the combined DCE-MRI and susceptibility contrast MRI assay with a blood pool agent in chara …
Quantification of breast tumor microvascular permeability with feruglose-enhanced MR imaging: initial phase II multicenter trial.
Daldrup-Link HE, Rydland J, Helbich TH, Bjørnerud A, Turetschek K, Kvistad KA, Kaindl E, Link TM, Staudacher K, Shames D, Brasch RC, Haraldseth O, Rummeny EJ. Daldrup-Link HE, et al. Radiology. 2003 Dec;229(3):885-92. doi: 10.1148/radiol.2293021045. Epub 2003 Oct 23. Radiology. 2003. PMID: 14576446 Clinical Trial.
A two-compartment unidirectional kinetic model applied to the dynamic data yielded estimates of the endothelial transfer coefficient, KPS, and the fractional plasma volume of the tumors. ...A moderate yet statistically significant correlation between KPS and SBR sco
A two-compartment unidirectional kinetic model applied to the dynamic data yielded estimates of the endothelial transfer coefficient,
Quantification of renal perfusion using an intravascular contrast agent (part 1): results in a canine model.
Aumann S, Schoenberg SO, Just A, Briley-Saebo K, Bjørnerud A, Bock M, Brix G. Aumann S, et al. Magn Reson Med. 2003 Feb;49(2):276-87. doi: 10.1002/mrm.10380. Magn Reson Med. 2003. PMID: 12541248
A mean rBV value of 28 ml/100 g was found in the renal cortex, with a corresponding mean rBF value of 524 ml/100 g/min and an average MTT of about 3.4 s. Although there was a systematic difference between the absolute blood flow values determined by MRI and t
A mean rBV value of 28 ml/100 g was found in the renal cortex, with a corresponding mean rBF value of 524 ml/100 g/min and an
Assessment of myocardial blood volume and water exchange: theoretical considerations and in vivo results.
Bjørnerud A, Bjerner T, Johansson LO, Ahlström HK. Bjørnerud A, et al. Magn Reson Med. 2003 May;49(5):828-37. doi: 10.1002/mrm.10430. Magn Reson Med. 2003. PMID: 12704765
In the present study, the T(1) relaxation rates were measured in eight pigs in blood and myocardium using a Look-Locker sequence after repeated injections of the intravascular contrast agent NC100150. The selection of myocardial region of interest was automated based on …
In the present study, the T(1) relaxation rates were measured in eight pigs in blood and myocardium using a Look-Locker sequence afte …
Cerebral perfusion in perinatal hypoxia and resuscitation assessed by transcranial contrast-enhanced ultrasound and 3 T MRI in newborn pigs.
de Lange C, Brabrand K, Emblem KE, Bjornerud A, Løberg EM, Saugstad OD, Munkeby BH. de Lange C, et al. Invest Radiol. 2011 Nov;46(11):686-96. doi: 10.1097/RLI.0b013e3182266431. Invest Radiol. 2011. PMID: 21730873
Following are the perfusion parameters for CEUS: peak intensity (PI), area under the curve (AUC), time to peak (TTP), and upslope a and perfusion/diffusion parameters for MRI: relative cerebral blood volume, relative cerebral blood flow, mean transit time, and apparent dif …
Following are the perfusion parameters for CEUS: peak intensity (PI), area under the curve (AUC), time to peak (TTP), and upslope a a …
Clearance of iron oxide particles in rat liver: effect of hydrated particle size and coating material on liver metabolism.
Briley-Saebo KC, Johansson LO, Hustvedt SO, Haldorsen AG, Bjørnerud A, Fayad ZA, Ahlstrom HK. Briley-Saebo KC, et al. Invest Radiol. 2006 Jul;41(7):560-71. doi: 10.1097/01.rli.0000221321.90261.09. Invest Radiol. 2006. PMID: 16772849
Quantitative liver R2* values were obtained during a 63-day time period. The concentration of iron oxide particles in the liver was determined by relaxometry, and these values were used to calculate the particle half-lives in the liver. RESULTS: After the administration of …
Quantitative liver R2* values were obtained during a 63-day time period. The concentration of iron oxide particles in the liver was d …
Long-term imaging effects in rat liver after a single injection of an iron oxide nanoparticle based MR contrast agent.
Briley-Saebø K, Hustvedt SO, Haldorsen A, Bjørnerud A. Briley-Saebø K, et al. J Magn Reson Imaging. 2004 Oct;20(4):622-31. doi: 10.1002/jmri.20175. J Magn Reson Imaging. 2004. PMID: 15390223
For the lowest dose group, the degradation of the particles could be defined by a mono-exponential function with a half-life of eight days. For the 2 and 5 mg Fe/kg dose groups, the degradation was bi-exponential with a fast initial decay of seven to eight da …
For the lowest dose group, the degradation of the particles could be defined by a mono-exponential function with a half-life o …
In and ex vivo MR evaluation of acute myocardial ischemia in pigs by determining R1 in steady state after the administration of the intravascular contrast agent NC100150 injection.
Bjerner T, Johansson L, Wikström G, Ericsson A, Briley-Soebo K, Bjørnerud A, Ahlström H. Bjerner T, et al. Invest Radiol. 2004 Aug;39(8):479-86. doi: 10.1097/01.rli.0000128658.63611.b3. Invest Radiol. 2004. PMID: 15257209
R1 was measured using a Look-Locker sequence for 2 dose groups (2 mg Fe/kg bw, n = 4, and 5 mg Fe/kg bw, n = 5) and a control group (n = 3). RESULTS: A significant increase in R1 was found in perfused myocardium after contrast agent injection, in contrast to …
R1 was measured using a Look-Locker sequence for 2 dose groups (2 mg Fe/kg bw, n = 4, and 5 mg Fe/kg bw, n = 5) and a control …
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