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Relaxed specificity of matrix metalloproteinases (MMPS) and TIMP insensitivity of tumor necrosis factor-alpha (TNF-alpha) production suggest the major TNF-alpha converting enzyme is not an MMP.
Black RA, Durie FH, Otten-Evans C, Miller R, Slack JL, Lynch DH, Castner B, Mohler KM, Gerhart M, Johnson RS, Itoh Y, Okada Y, Nagase H. Black RA, et al. Biochem Biophys Res Commun. 1996 Aug 14;225(2):400-5. doi: 10.1006/bbrc.1996.1186. Biochem Biophys Res Commun. 1996. PMID: 8753775
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