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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP. Black RA, et al. Nature. 1997 Feb 20;385(6618):729-33. doi: 10.1038/385729a0. Nature. 1997. PMID: 9034190
An essential role for ectodomain shedding in mammalian development.
Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, Russell WE, Castner BJ, Johnson RS, Fitzner JN, Boyce RW, Nelson N, Kozlosky CJ, Wolfson MF, Rauch CT, Cerretti DP, Paxton RJ, March CJ, Black RA. Peschon JJ, et al. Among authors: black ra. Science. 1998 Nov 13;282(5392):1281-4. doi: 10.1126/science.282.5392.1281. Science. 1998. PMID: 9812885
Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Maskos K, Fernandez-Catalan C, Huber R, Bourenkov GP, Bartunik H, Ellestad GA, Reddy P, Wolfson MF, Rauch CT, Castner BJ, Davis R, Clarke HR, Petersen M, Fitzner JN, Cerretti DP, March CJ, Paxton RJ, Black RA, Bode W. Maskos K, et al. Among authors: black ra. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3408-12. doi: 10.1073/pnas.95.7.3408. Proc Natl Acad Sci U S A. 1998. PMID: 9520379 Free PMC article.
257 results