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Ligand discovery and virtual screening using the program LIDAEUS.
Taylor P, Blackburn E, Sheng YG, Harding S, Hsin KY, Kan D, Shave S, Walkinshaw MD. Taylor P, et al. Br J Pharmacol. 2008 Mar;153 Suppl 1(Suppl 1):S55-67. doi: 10.1038/sj.bjp.0707532. Epub 2007 Nov 26. Br J Pharmacol. 2008. PMID: 18037921 Free PMC article. Review.
Targeting FKBP isoforms with small-molecule ligands.
Blackburn EA, Walkinshaw MD. Blackburn EA, et al. Curr Opin Pharmacol. 2011 Aug;11(4):365-71. doi: 10.1016/j.coph.2011.04.007. Epub 2011 Jul 29. Curr Opin Pharmacol. 2011. PMID: 21803654 Review.
The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers, and polymers with a folded back structure in solution.
Soares DC, Bradshaw NJ, Zou J, Kennaway CK, Hamilton RS, Chen ZA, Wear MA, Blackburn EA, Bramham J, Böttcher B, Millar JK, Barlow PN, Walkinshaw MD, Rappsilber J, Porteous DJ. Soares DC, et al. Among authors: blackburn ea. J Biol Chem. 2012 Sep 21;287(39):32381-93. doi: 10.1074/jbc.M112.393439. Epub 2012 Jul 27. J Biol Chem. 2012. PMID: 22843697 Free PMC article.
37 results