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101 results
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Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity.
Axon A, May FE, Gaughan LE, Williams FM, Blain PG, Wright MC. Axon A, et al. Among authors: blain pg. Toxicology. 2012 Aug 16;298(1-3):40-51. doi: 10.1016/j.tox.2012.04.014. Epub 2012 May 3. Toxicology. 2012. PMID: 22562034
Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation.
Amer AO, Probert PM, Dunn M, Knight M, Vallance AE, Flecknell PA, Oakley F, Cameron I, White SA, Blain PG, Wright MC. Amer AO, et al. Among authors: blain pg. PLoS One. 2015 Aug 24;10(8):e0136173. doi: 10.1371/journal.pone.0136173. eCollection 2015. PLoS One. 2015. PMID: 26302150 Free PMC article.
Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse.
Meyer SK, Probert PME, Lakey AF, Axon AR, Leitch AC, Williams FM, Jowsey PA, Blain PG, Kass GEN, Wright MC. Meyer SK, et al. Among authors: blain pg. Toxicol Lett. 2017 May 5;273:55-68. doi: 10.1016/j.toxlet.2017.03.024. Epub 2017 Mar 27. Toxicol Lett. 2017. PMID: 28356238 Free PMC article.
Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis.
Probert PM, Leitch AC, Dunn MP, Meyer SK, Palmer JM, Abdelghany TM, Lakey AF, Cooke MP, Talbot H, Wills C, McFarlane W, Blake LI, Rosenmai AK, Oskarsson A, Figueiredo R, Wilson C, Kass GE, Jones DE, Blain PG, Wright MC. Probert PM, et al. Among authors: blain pg. J Hepatol. 2018 Nov;69(5):1123-1135. doi: 10.1016/j.jhep.2018.06.027. Epub 2018 Jul 11. J Hepatol. 2018. PMID: 30006067 Free PMC article.
The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha.
Leitch AC, Lakey AF, Hotham WE, Agius L, Kass GEN, Blain PG, Wright MC. Leitch AC, et al. Among authors: blain pg. Biochem Biophys Res Commun. 2018 Sep 10;503(3):2167-2172. doi: 10.1016/j.bbrc.2018.08.008. Epub 2018 Aug 4. Biochem Biophys Res Commun. 2018. PMID: 30086880
Checkpoint kinase 1 is activated and promotes cell survival after exposure to sulphur mustard.
Jowsey PA, Blain PG. Jowsey PA, et al. Among authors: blain pg. Toxicol Lett. 2015 Jan 22;232(2):413-21. doi: 10.1016/j.toxlet.2014.11.013. Epub 2014 Nov 18. Toxicol Lett. 2015. PMID: 25448276
DNA damage responses in cells exposed to sulphur mustard.
Jowsey PA, Williams FM, Blain PG. Jowsey PA, et al. Among authors: blain pg. Toxicol Lett. 2012 Feb 25;209(1):1-10. doi: 10.1016/j.toxlet.2011.11.009. Epub 2011 Nov 18. Toxicol Lett. 2012. PMID: 22119920
Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?
Mutch E, Daly AK, Leathart JB, Blain PG, Williams FM. Mutch E, et al. Among authors: blain pg. Arch Toxicol. 2003 Jun;77(6):313-20. doi: 10.1007/s00204-003-0452-0. Epub 2003 Mar 21. Arch Toxicol. 2003. PMID: 12669189
DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide.
Jowsey PA, Williams FM, Blain PG. Jowsey PA, et al. Among authors: blain pg. Toxicology. 2009 Mar 29;257(3):105-12. doi: 10.1016/j.tox.2008.12.001. Epub 2008 Dec 6. Toxicology. 2009. PMID: 19111594
Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes.
Meyer SK, Probert PM, Lakey AK, Leitch AC, Blake LI, Jowsey PA, Cooke MP, Blain PG, Wright MC. Meyer SK, et al. Among authors: blain pg. Toxicol Sci. 2017 Mar 1;156(1):54-71. doi: 10.1093/toxsci/kfw234. Toxicol Sci. 2017. PMID: 28013213 Free PMC article.
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