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Naturally Produced Defensive Alkenal Compounds Activate TRPA1.
Blair NT, Philipson BI, Richards PM, Doerner JF, Segura A, Silver WL, Clapham DE. Blair NT, et al. Chem Senses. 2016 May;41(4):281-92. doi: 10.1093/chemse/bjv071. Epub 2016 Feb 3. Chem Senses. 2016. PMID: 26843529 Free PMC article.
Characterization of a Ca2+ release-activated nonselective cation current regulating membrane potential and [Ca2+]i oscillations in transgenically derived beta-cells.
Roe MW, Worley JF 3rd, Qian F, Tamarina N, Mittal AA, Dralyuk F, Blair NT, Mertz RJ, Philipson LH, Dukes ID. Roe MW, et al. Among authors: Blair NT. J Biol Chem. 1998 Apr 24;273(17):10402-10. doi: 10.1074/jbc.273.17.10402. J Biol Chem. 1998. PMID: 9553098 Free article.
Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling.
Roe MW, Worley JF 3rd, Mittal AA, Kuznetsov A, DasGupta S, Mertz RJ, Witherspoon SM 3rd, Blair N, Lancaster ME, McIntyre MS, Shehee WR, Dukes ID, Philipson LH. Roe MW, et al. Among authors: Blair N. J Biol Chem. 1996 Dec 13;271(50):32241-6. doi: 10.1074/jbc.271.50.32241. J Biol Chem. 1996. PMID: 8943282
Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.
Just S, Chenard BL, Ceci A, Strassmaier T, Chong JA, Blair NT, Gallaschun RJ, Del Camino D, Cantin S, D'Amours M, Eickmeier C, Fanger CM, Hecker C, Hessler DP, Hengerer B, Kroker KS, Malekiani S, Mihalek R, McLaughlin J, Rast G, Witek J, Sauer A, Pryce CR, Moran MM. Just S, et al. Among authors: Blair NT. PLoS One. 2018 Jan 31;13(1):e0191225. doi: 10.1371/journal.pone.0191225. eCollection 2018. PLoS One. 2018. PMID: 29385160 Free PMC article.
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