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Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation.
Jayanthi LD, Samuvel DJ, Blakely RD, Ramamoorthy S. Jayanthi LD, et al. Among authors: blakely rd. Mol Pharmacol. 2005 Jun;67(6):2077-87. doi: 10.1124/mol.104.009555. Epub 2005 Mar 17. Mol Pharmacol. 2005. PMID: 15774771
Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors.
Zhu CB, Lindler KM, Campbell NG, Sutcliffe JS, Hewlett WA, Blakely RD. Zhu CB, et al. Among authors: blakely rd. Mol Pharmacol. 2011 Sep;80(3):458-65. doi: 10.1124/mol.111.071399. Epub 2011 Jun 24. Mol Pharmacol. 2011. PMID: 21705486 Free PMC article.
Desvenlafaxine succinate identifies novel antagonist binding determinants in the human norepinephrine transporter.
Mason JN, Deecher DC, Richmond RL, Stack G, Mahaney PE, Trybulski E, Winneker RC, Blakely RD. Mason JN, et al. Among authors: blakely rd. J Pharmacol Exp Ther. 2007 Nov;323(2):720-9. doi: 10.1124/jpet.107.125716. Epub 2007 Aug 2. J Pharmacol Exp Ther. 2007. PMID: 17673606
Single nucleotide polymorphisms in the human norepinephrine transporter gene affect expression, trafficking, antidepressant interaction, and protein kinase C regulation.
Hahn MK, Mazei-Robison MS, Blakely RD. Hahn MK, et al. Among authors: blakely rd. Mol Pharmacol. 2005 Aug;68(2):457-66. doi: 10.1124/mol.105.011270. Epub 2005 May 13. Mol Pharmacol. 2005. PMID: 15894713
Stimulation of serotonin transport by the cyclic GMP phosphodiesterase-5 inhibitor sildenafil.
Zhu CB, Hewlett WA, Francis SH, Corbin JD, Blakely RD. Zhu CB, et al. Among authors: blakely rd. Eur J Pharmacol. 2004 Nov 3;504(1-2):1-6. doi: 10.1016/j.ejphar.2004.09.023. Eur J Pharmacol. 2004. PMID: 15507214
Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.
Zhu CB, Hewlett WA, Feoktistov I, Biaggioni I, Blakely RD. Zhu CB, et al. Among authors: blakely rd. Mol Pharmacol. 2004 Jun;65(6):1462-74. doi: 10.1124/mol.65.6.1462. Mol Pharmacol. 2004. PMID: 15155839
Calcium-dependent inhibition of synaptosomal serotonin transport by the alpha 2-adrenoceptor agonist 5-bromo-N-[4,5-dihydro-1H-imidazol-2-yl]-6-quinoxalinamine (UK14304).
Ansah TA, Ramamoorthy S, Montañez S, Daws LC, Blakely RD. Ansah TA, et al. Among authors: blakely rd. J Pharmacol Exp Ther. 2003 Jun;305(3):956-65. doi: 10.1124/jpet.102.047134. Epub 2003 Mar 6. J Pharmacol Exp Ther. 2003. PMID: 12626658
Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression.
Qian Y, Galli A, Ramamoorthy S, Risso S, DeFelice LJ, Blakely RD. Qian Y, et al. Among authors: blakely rd. J Neurosci. 1997 Jan 1;17(1):45-57. doi: 10.1523/JNEUROSCI.17-01-00045.1997. J Neurosci. 1997. PMID: 8987735 Free PMC article.
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