Phi 29 DNA polymerase active site. Mutants in conserved residues Tyr254 and Tyr390 are affected in dNTP binding.
Blasco MA, Lázaro JM, Bernad A, Blanco L, Salas M.
Blasco MA, et al. Among authors: blanco l.
J Biol Chem. 1992 Sep 25;267(27):19427-34.
J Biol Chem. 1992.
PMID: 1527062
Free article.
Among them, the two conserved regions characterized by the amino acid motifs "D-NSLYP" and "K--NS(L/V)YG," regions 1 and 2a, respectively, according to Blanco et al. (Blanco, L., Bernad, A., Blasco, M. A. and Salas, M. (1991) Gene (Amst.) 100, 27-38) h …
Among them, the two conserved regions characterized by the amino acid motifs "D-NSLYP" and "K--NS(L/V)YG," regions 1 and 2a, respecti …