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Endoplasmic Reticulum and Mitochondria: Independent Roles and Crosstalk in Fatty Liver Diseases and Hepatic Inflammation.
Blas-García A, Apostolova N, Valls-Bellés V, Esplugues JV. Blas-García A, et al. Curr Pharm Des. 2016;22(18):2607-18. doi: 10.2174/1381612822666160204120354. Curr Pharm Des. 2016. PMID: 26845326 Review.
Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells.
Blas-García A, Apostolova N, Ballesteros D, Monleón D, Morales JM, Rocha M, Victor VM, Esplugues JV. Blas-García A, et al. Hepatology. 2010 Jul;52(1):115-25. doi: 10.1002/hep.23647. Hepatology. 2010. PMID: 20564379
Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells.
Apostolova N, Gomez-Sucerquia LJ, Moran A, Alvarez A, Blas-Garcia A, Esplugues JV. Apostolova N, et al. Br J Pharmacol. 2010 Aug;160(8):2069-84. doi: 10.1111/j.1476-5381.2010.00866.x. Br J Pharmacol. 2010. PMID: 20649602 Free PMC article.
Twenty years of HIV-1 non-nucleoside reverse transcriptase inhibitors: time to reevaluate their toxicity.
Blas-Garcia A, Esplugues JV, Apostolova N. Blas-Garcia A, et al. Curr Med Chem. 2011;18(14):2186-95. doi: 10.2174/092986711795656180. Curr Med Chem. 2011. PMID: 21521162 Review.
Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy.
Apostolova N, Gomez-Sucerquia LJ, Gortat A, Blas-Garcia A, Esplugues JV. Apostolova N, et al. Hepatology. 2011 Sep 2;54(3):1009-19. doi: 10.1002/hep.24459. Epub 2011 Aug 2. Hepatology. 2011. PMID: 21626526
Mitochondrial toxicity in HAART: an overview of in vitro evidence.
Apostolova N, Blas-García A, Esplugues JV. Apostolova N, et al. Curr Pharm Des. 2011;17(20):2130-44. doi: 10.2174/138161211796904731. Curr Pharm Des. 2011. PMID: 21718249 Review.
Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition.
Apostolova N, Blas-García A, Esplugues JV. Apostolova N, et al. Trends Pharmacol Sci. 2011 Dec;32(12):715-25. doi: 10.1016/j.tips.2011.07.007. Epub 2011 Sep 6. Trends Pharmacol Sci. 2011. PMID: 21899897 Review.
Autophagy as a rescue mechanism in efavirenz-induced mitochondrial dysfunction: a lesson from hepatic cells.
Apostolova N, Gomez-Sucerquia LJ, Gortat A, Blas-Garcia A, Esplugues JV. Apostolova N, et al. Autophagy. 2011 Nov;7(11):1402-4. doi: 10.4161/auto.7.11.17653. Epub 2011 Nov 1. Autophagy. 2011. PMID: 21997370
Mitochondria sentencing about cellular life and death: a matter of oxidative stress.
Apostolova N, Blas-Garcia A, Esplugues JV. Apostolova N, et al. Curr Pharm Des. 2011 Dec 1;17(36):4047-60. doi: 10.2174/138161211798764924. Curr Pharm Des. 2011. PMID: 22188454 Review.
Oxidative stress and mitochondrial impairment after treatment with anti-HIV drugs: clinical implications.
Blas-Garcia A, Apostolova N, Esplugues JV. Blas-Garcia A, et al. Curr Pharm Des. 2011 Dec 1;17(36):4076-86. doi: 10.2174/138161211798764951. Curr Pharm Des. 2011. PMID: 22188456 Review.
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