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Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development.
Blaschke RJ, Hahurij ND, Kuijper S, Just S, Wisse LJ, Deissler K, Maxelon T, Anastassiadis K, Spitzer J, Hardt SE, Schöler H, Feitsma H, Rottbauer W, Blum M, Meijlink F, Rappold G, Gittenberger-de Groot AC. Blaschke RJ, et al. Circulation. 2007 Apr 10;115(14):1830-8. doi: 10.1161/CIRCULATIONAHA.106.637819. Epub 2007 Mar 19. Circulation. 2007. PMID: 17372176
The short stature homeodomain protein SHOX induces cellular growth arrest and apoptosis and is expressed in human growth plate chondrocytes.
Marchini A, Marttila T, Winter A, Caldeira S, Malanchi I, Blaschke RJ, Häcker B, Rao E, Karperien M, Wit JM, Richter W, Tommasino M, Rappold GA. Marchini A, et al. Among authors: blaschke rj. J Biol Chem. 2004 Aug 27;279(35):37103-14. doi: 10.1074/jbc.M307006200. Epub 2004 May 15. J Biol Chem. 2004. PMID: 15145945 Free article.
The pseudoautosomal regions, SHOX and disease.
Blaschke RJ, Rappold G. Blaschke RJ, et al. Curr Opin Genet Dev. 2006 Jun;16(3):233-9. doi: 10.1016/j.gde.2006.04.004. Epub 2006 May 2. Curr Opin Genet Dev. 2006. PMID: 16650979 Review.
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