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Telomere length, stem cells and aging.
Blasco MA. Blasco MA. Nat Chem Biol. 2007 Oct;3(10):640-9. doi: 10.1038/nchembio.2007.38. Nat Chem Biol. 2007. PMID: 17876321 Review.
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA.
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW. Blasco MA, et al. Cell. 1997 Oct 3;91(1):25-34. doi: 10.1016/s0092-8674(01)80006-4. Cell. 1997. PMID: 9335332
Essential role of mouse telomerase in highly proliferative organs.
Lee HW, Blasco MA, Gottlieb GJ, Horner JW 2nd, Greider CW, DePinho RA. Lee HW, et al. Among authors: blasco ma. Nature. 1998 Apr 9;392(6676):569-74. doi: 10.1038/33345. Nature. 1998. PMID: 9560153
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice.
Hande MP, Samper E, Lansdorp P, Blasco MA. Hande MP, et al. Among authors: blasco ma. J Cell Biol. 1999 Feb 22;144(4):589-601. doi: 10.1083/jcb.144.4.589. J Cell Biol. 1999. PMID: 10037783 Free PMC article.
Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube.
Herrera E, Samper E, Blasco MA. Herrera E, et al. Among authors: blasco ma. EMBO J. 1999 Mar 1;18(5):1172-81. doi: 10.1093/emboj/18.5.1172. EMBO J. 1999. PMID: 10064584 Free PMC article.
Telomere-dependent senescence.
Kipling D, Wynford-Thomas D, Jones CJ, Akbar A, Aspinall R, Bacchetti S, Blasco MA, Broccoli D, DePinho RA, Edwards DR, Effros RB, Harley CB, Lansdorp PM, Linskens MH, Prowse KR, Newbold RF, Olovnikov AM, Parkinson EK, Pawelec G, Pontén J, Shall S, Zijlmans M, Faragher RG. Kipling D, et al. Among authors: blasco ma. Nat Biotechnol. 1999 Apr;17(4):313-4. doi: 10.1038/7827. Nat Biotechnol. 1999. PMID: 10207859 No abstract available.
Disease states associated with telomerase deficiency appear earlier in mice with short telomeres.
Herrera E, Samper E, Martín-Caballero J, Flores JM, Lee HW, Blasco MA. Herrera E, et al. Among authors: blasco ma. EMBO J. 1999 Jun 1;18(11):2950-60. doi: 10.1093/emboj/18.11.2950. EMBO J. 1999. PMID: 10357808 Free PMC article.
Telomeres and telomerase.
Blasco MA, Gasser SM, Lingner J. Blasco MA, et al. Genes Dev. 1999 Sep 15;13(18):2353-9. doi: 10.1101/gad.13.18.2353. Genes Dev. 1999. PMID: 10500091 No abstract available.
Impaired germinal center reaction in mice with short telomeres.
Herrera E, Martínez-A C, Blasco MA. Herrera E, et al. Among authors: blasco ma. EMBO J. 2000 Feb 1;19(3):472-81. doi: 10.1093/emboj/19.3.472. EMBO J. 2000. PMID: 10654945 Free PMC article.
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.
González-Suárez E, Samper E, Flores JM, Blasco MA. González-Suárez E, et al. Among authors: blasco ma. Nat Genet. 2000 Sep;26(1):114-7. doi: 10.1038/79089. Nat Genet. 2000. PMID: 10973262
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