Blattner C - Search Results

1

Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth.

Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo SX, Low DH, Koh CM, Rambow F, Fiers M, Rogiers A, Radaelli E, Al-Haddawi M, Tan SY, Hermans E, Amant F, Yan H, Lakshmanan M, Koumar RC, Lim ST, Derheimer FA, Campbell RM, Bonday Z, Tergaonkar V, Shackleton M, Blattner C, Marine JC, Guccione E. Dewaele M, et al. Among authors: blattner c. J Clin Invest. 2016 Jan;126(1):68-84. doi: 10.1172/JCI82534. Epub 2015 Nov 23. J Clin Invest. 2016. PMID: 26595814 Free PMC article.

2

p53 is active in murine stem cells and alters the transcriptome in a manner that is reminiscent of mutant p53.

Yan H, Solozobova V, Zhang P, Armant O, Kuehl B, Brenner-Weiss G, Blattner C. Yan H, et al. Among authors: blattner c. Cell Death Dis. 2015 Feb 26;6(2):e1662. doi: 10.1038/cddis.2015.33. Cell Death Dis. 2015. PMID: 25719246 Free PMC article.

3

TRIM25 has a dual function in the p53/Mdm2 circuit.

Zhang P, Elabd S, Hammer S, Solozobova V, Yan H, Bartel F, Inoue S, Henrich T, Wittbrodt J, Loosli F, Davidson G, Blattner C. Zhang P, et al. Among authors: blattner c. Oncogene. 2015 Nov 12;34(46):5729-38. doi: 10.1038/onc.2015.21. Epub 2015 Mar 2. Oncogene. 2015. PMID: 25728675

4

Photoproducts in transcriptionally active DNA induce signal transduction to the delayed U.V.-responsive genes for collagenase and metallothionein.

Blattner C, Bender K, Herrlich P, Rahmsdorf HJ. Blattner C, et al. Oncogene. 1998 Jun 4;16(22):2827-34. doi: 10.1038/sj.onc.1201827. Oncogene. 1998. PMID: 9671403

5

DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation.

Blattner C, Tobiasch E, Litfen M, Rahmsdorf HJ, Herrlich P. Blattner C, et al. Oncogene. 1999 Mar 4;18(9):1723-32. doi: 10.1038/sj.onc.1202480. Oncogene. 1999. PMID: 10208433

6

Hypophosphorylation of Mdm2 augments p53 stability.

Blattner C, Hay T, Meek DW, Lane DP. Blattner C, et al. Mol Cell Biol. 2002 Sep;22(17):6170-82. doi: 10.1128/MCB.22.17.6170-6182.2002. Mol Cell Biol. 2002. PMID: 12167711 Free PMC article.

7

Protein kinase CK1delta phosphorylates key sites in the acidic domain of murine double-minute clone 2 protein (MDM2) that regulate p53 turnover.

Winter M, Milne D, Dias S, Kulikov R, Knippschild U, Blattner C, Meek D. Winter M, et al. Among authors: blattner c. Biochemistry. 2004 Dec 28;43(51):16356-64. doi: 10.1021/bi0489255. Biochemistry. 2004. PMID: 15610030

8

Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance.

Kulikov R, Boehme KA, Blattner C. Kulikov R, et al. Among authors: blattner c. Mol Cell Biol. 2005 Aug;25(16):7170-80. doi: 10.1128/MCB.25.16.7170-7180.2005. Mol Cell Biol. 2005. PMID: 16055726 Free PMC article.

9

Binding of p53 to the central domain of Mdm2 is regulated by phosphorylation.

Kulikov R, Winter M, Blattner C. Kulikov R, et al. Among authors: blattner c. J Biol Chem. 2006 Sep 29;281(39):28575-83. doi: 10.1074/jbc.M513311200. Epub 2006 Jul 26. J Biol Chem. 2006. PMID: 16870621 Free article.

10

p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.

Boehme KA, Kulikov R, Blattner C. Boehme KA, et al. Among authors: blattner c. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7785-90. doi: 10.1073/pnas.0703423105. Epub 2008 May 27. Proc Natl Acad Sci U S A. 2008. PMID: 18505846 Free PMC article.

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