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ACET is a highly potent and specific kainate receptor antagonist: characterisation and effects on hippocampal mossy fibre function.
Dargan SL, Clarke VR, Alushin GM, Sherwood JL, Nisticò R, Bortolotto ZA, Ogden AM, Bleakman D, Doherty AJ, Lodge D, Mayer ML, Fitzjohn SM, Jane DE, Collingridge GL. Dargan SL, et al. Among authors: bleakman d. Neuropharmacology. 2009 Jan;56(1):121-30. doi: 10.1016/j.neuropharm.2008.08.016. Epub 2008 Aug 22. Neuropharmacology. 2009. PMID: 18789344 Free PMC article.
Kainate receptors are involved in synaptic plasticity.
Bortolotto ZA, Clarke VR, Delany CM, Parry MC, Smolders I, Vignes M, Ho KH, Miu P, Brinton BT, Fantaske R, Ogden A, Gates M, Ornstein PL, Lodge D, Bleakman D, Collingridge GL. Bortolotto ZA, et al. Among authors: bleakman d. Nature. 1999 Nov 18;402(6759):297-301. doi: 10.1038/46290. Nature. 1999. PMID: 10580501
Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist.
More JC, Nistico R, Dolman NP, Clarke VR, Alt AJ, Ogden AM, Buelens FP, Troop HM, Kelland EE, Pilato F, Bleakman D, Bortolotto ZA, Collingridge GL, Jane DE. More JC, et al. Among authors: bleakman d. Neuropharmacology. 2004 Jul;47(1):46-64. doi: 10.1016/j.neuropharm.2004.03.005. Neuropharmacology. 2004. PMID: 15165833
A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission.
Clarke VR, Ballyk BA, Hoo KH, Mandelzys A, Pellizzari A, Bath CP, Thomas J, Sharpe EF, Davies CH, Ornstein PL, Schoepp DD, Kamboj RK, Collingridge GL, Lodge D, Bleakman D. Clarke VR, et al. Among authors: bleakman d. Nature. 1997 Oct 9;389(6651):599-603. doi: 10.1038/39315. Nature. 1997. PMID: 9335499
92 results