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Neuropharmacology of AMPA and kainate receptors.
Bleakman D, Lodge D. Bleakman D, et al. Neuropharmacology. 1998 Oct-Nov;37(10-11):1187-204. doi: 10.1016/s0028-3908(98)00139-7. Neuropharmacology. 1998. PMID: 9849657 Review. No abstract available.
Pharmacological characterization of the competitive GLUK5 receptor antagonist decahydroisoquinoline LY466195 in vitro and in vivo.
Weiss B, Alt A, Ogden AM, Gates M, Dieckman DK, Clemens-Smith A, Ho KH, Jarvie K, Rizkalla G, Wright RA, Calligaro DO, Schoepp D, Mattiuz EL, Stratford RE, Johnson B, Salhoff C, Katofiasc M, Phebus LA, Schenck K, Cohen M, Filla SA, Ornstein PL, Johnson KW, Bleakman D. Weiss B, et al. Among authors: bleakman d. J Pharmacol Exp Ther. 2006 Aug;318(2):772-81. doi: 10.1124/jpet.106.101428. Epub 2006 May 11. J Pharmacol Exp Ther. 2006. PMID: 16690725
A role for AMPA receptors in mood disorders.
Alt A, Nisenbaum ES, Bleakman D, Witkin JM. Alt A, et al. Among authors: bleakman d. Biochem Pharmacol. 2006 Apr 28;71(9):1273-88. doi: 10.1016/j.bcp.2005.12.022. Epub 2006 Jan 24. Biochem Pharmacol. 2006. PMID: 16442080 Review.
AMPA receptor potentiators for the treatment of CNS disorders.
O'Neill MJ, Bleakman D, Zimmerman DM, Nisenbaum ES. O'Neill MJ, et al. Among authors: bleakman d. Curr Drug Targets CNS Neurol Disord. 2004 Jun;3(3):181-94. doi: 10.2174/1568007043337508. Curr Drug Targets CNS Neurol Disord. 2004. PMID: 15180479 Review.
LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.
Murray TK, Whalley K, Robinson CS, Ward MA, Hicks CA, Lodge D, Vandergriff JL, Baumbarger P, Siuda E, Gates M, Ogden AM, Skolnick P, Zimmerman DM, Nisenbaum ES, Bleakman D, O'Neill MJ. Murray TK, et al. Among authors: bleakman d. J Pharmacol Exp Ther. 2003 Aug;306(2):752-62. doi: 10.1124/jpet.103.049445. Epub 2003 May 2. J Pharmacol Exp Ther. 2003. PMID: 12730350
Design and synthesis of a novel series of 1,2-disubstituted cyclopentanes as small, potent potentiators of 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid (AMPA) receptors.
Shepherd TA, Aikins JA, Bleakman D, Cantrell BE, Rearick JP, Simon RL, Smith EC, Stephenson GA, Zimmerman DM, Mandelzys A, Jarvie KR, Ho K, Deverill M, Kamboj RK. Shepherd TA, et al. Among authors: bleakman d. J Med Chem. 2002 May 9;45(10):2101-11. doi: 10.1021/jm0105474. J Med Chem. 2002. PMID: 11985477
Glutamate receptors and pain.
Bleakman D, Alt A, Nisenbaum ES. Bleakman D, et al. Semin Cell Dev Biol. 2006 Oct;17(5):592-604. doi: 10.1016/j.semcdb.2006.10.008. Epub 2006 Oct 28. Semin Cell Dev Biol. 2006. PMID: 17110139 Review.
91 results