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Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
Pataskar A, Champagne J, Nagel R, Kenski J, Laos M, Michaux J, Pak HS, Bleijerveld OB, Mordente K, Navarro JM, Blommaert N, Nielsen MM, Lovecchio D, Stone E, Georgiou G, de Gooijer MC, van Tellingen O, Altelaar M, Joosten RP, Perrakis A, Olweus J, Bassani-Sternberg M, Peeper DS, Agami R. Pataskar A, et al. Among authors: bleijerveld ob. Nature. 2022 Mar;603(7902):721-727. doi: 10.1038/s41586-022-04499-2. Epub 2022 Mar 9. Nature. 2022. PMID: 35264796 Free PMC article.
N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids.
Jansen RS, Addie R, Merkx R, Fish A, Mahakena S, Bleijerveld OB, Altelaar M, IJlst L, Wanders RJ, Borst P, van de Wetering K. Jansen RS, et al. Among authors: bleijerveld ob. Proc Natl Acad Sci U S A. 2015 May 26;112(21):6601-6. doi: 10.1073/pnas.1424638112. Epub 2015 May 11. Proc Natl Acad Sci U S A. 2015. PMID: 25964343 Free PMC article.
BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.
Kemper K, Krijgsman O, Kong X, Cornelissen-Steijger P, Shahrabi A, Weeber F, van der Velden DL, Bleijerveld OB, Kuilman T, Kluin RJC, Sun C, Voest EE, Ju YS, Schumacher TNM, Altelaar AFM, McDermott U, Adams DJ, Blank CU, Haanen JB, Peeper DS. Kemper K, et al. Among authors: bleijerveld ob. Cell Rep. 2016 Jun 28;16(1):263-277. doi: 10.1016/j.celrep.2016.05.064. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320919 Free PMC article.
Vasohibins encode tubulin detyrosinating activity.
Nieuwenhuis J, Adamopoulos A, Bleijerveld OB, Mazouzi A, Stickel E, Celie P, Altelaar M, Knipscheer P, Perrakis A, Blomen VA, Brummelkamp TR. Nieuwenhuis J, et al. Among authors: bleijerveld ob. Science. 2017 Dec 15;358(6369):1453-1456. doi: 10.1126/science.aao5676. Epub 2017 Nov 16. Science. 2017. PMID: 29146869
Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.
Adamopoulos A, Landskron L, Heidebrecht T, Tsakou F, Bleijerveld OB, Altelaar M, Nieuwenhuis J, Celie PHN, Brummelkamp TR, Perrakis A. Adamopoulos A, et al. Among authors: bleijerveld ob. Nat Struct Mol Biol. 2019 Jul;26(7):567-570. doi: 10.1038/s41594-019-0254-6. Epub 2019 Jul 1. Nat Struct Mol Biol. 2019. PMID: 31270470
Anti-tumour immunity induces aberrant peptide presentation in melanoma.
Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Körner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang X, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang W, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR, Geiger T, Peeper DS, Olweus J, Samuels Y, Agami R. Bartok O, et al. Among authors: bleijerveld ob. Nature. 2021 Feb;590(7845):332-337. doi: 10.1038/s41586-020-03054-1. Epub 2020 Dec 16. Nature. 2021. PMID: 33328638
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.
Li L, Ugalde AP, Scheele CLGJ, Dieter SM, Nagel R, Ma J, Pataskar A, Korkmaz G, Elkon R, Chien MP, You L, Su PR, Bleijerveld OB, Altelaar M, Momchev L, Manber Z, Han R, van Breugel PC, Lopes R, Ten Dijke P, van Rheenen J, Agami R. Li L, et al. Among authors: bleijerveld ob. Genome Biol. 2021 Jan 29;22(1):54. doi: 10.1186/s13059-021-02272-8. Genome Biol. 2021. PMID: 33514403 Free PMC article.
Oncogene-dependent sloppiness in mRNA translation.
Champagne J, Pataskar A, Blommaert N, Nagel R, Wernaart D, Ramalho S, Kenski J, Bleijerveld OB, Zaal EA, Berkers CR, Altelaar M, Peeper DS, Faller WJ, Agami R. Champagne J, et al. Among authors: bleijerveld ob. Mol Cell. 2021 Nov 18;81(22):4709-4721.e9. doi: 10.1016/j.molcel.2021.09.002. Epub 2021 Sep 24. Mol Cell. 2021. PMID: 34562372 Free article.
42 results