Block SM - Search Results

1

Sequence-resolved detection of pausing by single RNA polymerase molecules.

Herbert KM, La Porta A, Wong BJ, Mooney RA, Neuman KC, Landick R, Block SM. Herbert KM, et al. Among authors: block sm. Cell. 2006 Jun 16;125(6):1083-94. doi: 10.1016/j.cell.2006.04.032. Cell. 2006. PMID: 16777599 Free PMC article.

2

Backtracking by single RNA polymerase molecules observed at near-base-pair resolution.

Shaevitz JW, Abbondanzieri EA, Landick R, Block SM. Shaevitz JW, et al. Among authors: block sm. Nature. 2003 Dec 11;426(6967):684-7. doi: 10.1038/nature02191. Epub 2003 Nov 23. Nature. 2003. PMID: 14634670 Free PMC article.

3

Direct observation of base-pair stepping by RNA polymerase.

Abbondanzieri EA, Greenleaf WJ, Shaevitz JW, Landick R, Block SM. Abbondanzieri EA, et al. Among authors: block sm. Nature. 2005 Nov 24;438(7067):460-5. doi: 10.1038/nature04268. Epub 2005 Nov 13. Nature. 2005. PMID: 16284617 Free PMC article.

4

Pulling on the nascent RNA during transcription does not alter kinetics of elongation or ubiquitous pausing.

Dalal RV, Larson MH, Neuman KC, Gelles J, Landick R, Block SM. Dalal RV, et al. Among authors: block sm. Mol Cell. 2006 Jul 21;23(2):231-9. doi: 10.1016/j.molcel.2006.06.023. Mol Cell. 2006. PMID: 16857589 Free PMC article.

5

Applied force reveals mechanistic and energetic details of transcription termination.

Larson MH, Greenleaf WJ, Landick R, Block SM. Larson MH, et al. Among authors: block sm. Cell. 2008 Mar 21;132(6):971-82. doi: 10.1016/j.cell.2008.01.027. Cell. 2008. PMID: 18358810 Free PMC article.

6

Single-molecule studies of RNA polymerase: motoring along.

Herbert KM, Greenleaf WJ, Block SM. Herbert KM, et al. Among authors: block sm. Annu Rev Biochem. 2008;77:149-76. doi: 10.1146/annurev.biochem.77.073106.100741. Annu Rev Biochem. 2008. PMID: 18410247 Free PMC article. Review.

7

E. coli NusG inhibits backtracking and accelerates pause-free transcription by promoting forward translocation of RNA polymerase.

Herbert KM, Zhou J, Mooney RA, Porta AL, Landick R, Block SM. Herbert KM, et al. Among authors: block sm. J Mol Biol. 2010 May 28;399(1):17-30. doi: 10.1016/j.jmb.2010.03.051. Epub 2010 Apr 8. J Mol Biol. 2010. PMID: 20381500 Free PMC article.

8

Single-molecule studies of RNA polymerase: one singular sensation, every little step it takes.

Larson MH, Landick R, Block SM. Larson MH, et al. Among authors: block sm. Mol Cell. 2011 Feb 4;41(3):249-62. doi: 10.1016/j.molcel.2011.01.008. Mol Cell. 2011. PMID: 21292158 Free PMC article. Review.

9

Applied force provides insight into transcriptional pausing and its modulation by transcription factor NusA.

Zhou J, Ha KS, La Porta A, Landick R, Block SM. Zhou J, et al. Among authors: block sm. Mol Cell. 2011 Nov 18;44(4):635-46. doi: 10.1016/j.molcel.2011.09.018. Mol Cell. 2011. PMID: 22099310 Free PMC article.

10

Binding and translocation of termination factor rho studied at the single-molecule level.

Koslover DJ, Fazal FM, Mooney RA, Landick R, Block SM. Koslover DJ, et al. Among authors: block sm. J Mol Biol. 2012 Nov 9;423(5):664-76. doi: 10.1016/j.jmb.2012.07.027. Epub 2012 Aug 9. J Mol Biol. 2012. PMID: 22885804 Free PMC article.

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