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Health effects of diesel exhaust emissions.
Sydbom A, Blomberg A, Parnia S, Stenfors N, Sandström T, Dahlén SE. Sydbom A, et al. Eur Respir J. 2001 Apr;17(4):733-46. doi: 10.1183/09031936.01.17407330. Eur Respir J. 2001. PMID: 11401072 Review.
Of the motor vehicle generated air pollutants, diesel exhaust particles account for a highly significant percentage of the particles emitted in many towns and cities. ...In addition to symptoms, exposure studies in healthy humans have documented a number of profound …
Of the motor vehicle generated air pollutants, diesel exhaust particles account for a highly significant percentage of the particles …
Proteolytic biomarkers are related to prognosis in COPD- report from a population-based cohort.
Linder R, Rönmark E, Pourazar J, Behndig AF, Blomberg A, Lindberg A. Linder R, et al. Respir Res. 2018 Apr 12;19(1):64. doi: 10.1186/s12931-018-0772-5. Respir Res. 2018. PMID: 29650051 Free PMC article.
This was done among subjects with COPD in a population-based cohort. METHODS: In 2005, clinical examinations including spirometry and peripheral blood sampling, were made in a longitudinal population-based cohort. ...CONCLUSIONS: The expected association between the …
This was done among subjects with COPD in a population-based cohort. METHODS: In 2005, clinical examinations including spirometry and …
Bronchoalveolar matrix metalloproteinase 9 relates to restrictive lung function impairment in systemic sclerosis.
Andersen GN, Nilsson K, Pourazar J, Hackett TL, Kazzam E, Blomberg A, Waldenström A, Warner J, Rantapää-Dahlqvist S, Mincheva-Nilsson L, Sandström T. Andersen GN, et al. Respir Med. 2007 Oct;101(10):2199-206. doi: 10.1016/j.rmed.2007.04.019. Epub 2007 Jul 20. Respir Med. 2007. PMID: 17643278
The present study suggests that MMP-9 plays a pathophysiological role in the remodelling in ILD and lung fibrosis associated with SSc, and may represent a new therapeutic target in this condition....
The present study suggests that MMP-9 plays a pathophysiological role in the remodelling in ILD and lung fibrosis associated with SSc …
Assessment of the capacity of vehicle cabin air inlet filters to reduce diesel exhaust-induced symptoms in human volunteers.
Muala A, Sehlstedt M, Bion A, Osterlund C, Bosson JA, Behndig AF, Pourazar J, Bucht A, Boman C, Mudway IS, Langrish JP, Couderc S, Blomberg A, Sandström T. Muala A, et al. Environ Health. 2014 Mar 13;13(1):16. doi: 10.1186/1476-069X-13-16. Environ Health. 2014. PMID: 24621126 Free PMC article. Clinical Trial.
In parallel, PM were collected from unfiltered and filtered DE and assessed for their capacity to drive damaging oxidation reactions in a cell-free model, or promote inflammation in A549 cells. ...In addition use of the active charcoal filter was associated by a 75% …
In parallel, PM were collected from unfiltered and filtered DE and assessed for their capacity to drive damaging oxidation reactions in a
From COPD epidemiology to studies of pathophysiological disease mechanisms: challenges with regard to study design and recruitment process: Respiratory and Cardiovascular Effects in COPD (KOLIN).
Lindberg A, Linder R, Backman H, Eriksson Ström J, Frølich A, Nilsson U, Rönmark E, Johansson Strandkvist V, Behndig AF, Blomberg A. Lindberg A, et al. Eur Clin Respir J. 2017 Dec 17;4(1):1415095. doi: 10.1080/20018525.2017.1415095. eCollection 2017. Eur Clin Respir J. 2017. PMID: 29296255 Free PMC article.
Background: Chronic obstructive pulmonary disease (COPD) is a largely underdiagnosed disease including several phenotypes. In this report, the design of a study intending to evaluate the pathophysiological mechanism in COPD in relation to the specific phenotypes non …
Background: Chronic obstructive pulmonary disease (COPD) is a largely underdiagnosed disease including several phenotypes. In this re …
Central arterial stiffness is increased among subjects with severe and very severe COPD: report from a population-based cohort study.
Qvist L, Nilsson U, Johansson V, Larsson K, Rönmark E, Langrish J, Blomberg A, Lindberg A. Qvist L, et al. Eur Clin Respir J. 2015 Mar 16;2. doi: 10.3402/ecrj.v2.27023. eCollection 2015. Eur Clin Respir J. 2015. PMID: 26557263 Free PMC article.
Central arterial stiffness is a marker of early atherosclerosis, but the association between COPD, productive cough, and arterial stiffness as a possible indicator of CVD is unclear. ...METHODS: A population-based cohort, including 993 COPD and 993 non-COPD s …
Central arterial stiffness is a marker of early atherosclerosis, but the association between COPD, productive cough, and arterial sti …
Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study.
Carlsten C, Blomberg A, Pui M, Sandstrom T, Wong SW, Alexis N, Hirota J. Carlsten C, et al. Thorax. 2016 Jan;71(1):35-44. doi: 10.1136/thoraxjnl-2015-207399. Epub 2015 Nov 16. Thorax. 2016. PMID: 26574583
OBJECTIVE: To test the hypothesis that a 2 h inhalation of diesel exhaust augments lower airway inflammation and immune cell activation following segmental allergen challenge in atopic subjects. ...Allergic individuals are a susceptible population to the deleterious …
OBJECTIVE: To test the hypothesis that a 2 h inhalation of diesel exhaust augments lower airway inflammation and immune cell activati …
Diesel exhaust but not ozone increases fraction of exhaled nitric oxide in a randomized controlled experimental exposure study of healthy human subjects.
Barath S, Mills NL, Adelroth E, Olin AC, Blomberg A. Barath S, et al. Environ Health. 2013 Apr 20;12:36. doi: 10.1186/1476-069X-12-36. Environ Health. 2013. PMID: 23602059 Free PMC article.
BACKGROUND: Fraction of exhaled nitric oxide (FENO) is a promising non-invasive index of airway inflammation that may be used to assess respiratory effects of air pollution. We evaluated FENO as a measure of airway inflammation after controlled exposure to diesel ex …
BACKGROUND: Fraction of exhaled nitric oxide (FENO) is a promising non-invasive index of airway inflammation that may be used to asse …
Occupational lung diseases: from old and novel exposures to effective preventive strategies.
Cullinan P, Muñoz X, Suojalehto H, Agius R, Jindal S, Sigsgaard T, Blomberg A, Charpin D, Annesi-Maesano I, Gulati M, Kim Y, Frank AL, Akgün M, Fishwick D, de la Hoz RE, Moitra S. Cullinan P, et al. Lancet Respir Med. 2017 May;5(5):445-455. doi: 10.1016/S2213-2600(16)30424-6. Epub 2017 Jan 7. Lancet Respir Med. 2017. PMID: 28089118 Review.
Although the incidence of occupational lung disease has decreased in many countries, in parts of the world undergoing rapid economic transition and population growth-often with large informal and unregulated workforces-occupational exposures continue to impose a heavy burd …
Although the incidence of occupational lung disease has decreased in many countries, in parts of the world undergoing rapid economic transit …
Health impacts of anthropogenic biomass burning in the developed world.
Sigsgaard T, Forsberg B, Annesi-Maesano I, Blomberg A, Bølling A, Boman C, Bønløkke J, Brauer M, Bruce N, Héroux ME, Hirvonen MR, Kelly F, Künzli N, Lundbäck B, Moshammer H, Noonan C, Pagels J, Sallsten G, Sculier JP, Brunekreef B. Sigsgaard T, et al. Eur Respir J. 2015 Dec;46(6):1577-88. doi: 10.1183/13993003.01865-2014. Epub 2015 Sep 24. Eur Respir J. 2015. PMID: 26405285
Climate change policies have stimulated a shift towards renewable energy sources such as biomass. The economic crisis of 2008 has also increased the practice of household biomass burning as it is often cheaper than using oil, gas or electricity for heating. As a res …
Climate change policies have stimulated a shift towards renewable energy sources such as biomass. The economic crisis of 2008 has als …
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