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A yeast-based assay identifies drugs active against human mitochondrial disorders.
Couplan E, Aiyar RS, Kucharczyk R, Kabala A, Ezkurdia N, Gagneur J, St Onge RP, Salin B, Soubigou F, Le Cann M, Steinmetz LM, di Rago JP, Blondel M. Couplan E, et al. Among authors: blondel m. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11989-94. doi: 10.1073/pnas.1101478108. Epub 2011 Jun 29. Proc Natl Acad Sci U S A. 2011. PMID: 21715656 Free PMC article.
Using budding yeast to screen for anti-prion drugs.
Tribouillard D, Bach S, Gug F, Desban N, Beringue V, Andrieu T, Dormont D, Galons H, Laude H, Vilette D, Blondel M. Tribouillard D, et al. Among authors: blondel m. Biotechnol J. 2006 Jan;1(1):58-67. doi: 10.1002/biot.200500001. Biotechnol J. 2006. PMID: 16892225
Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs.
Tribouillard-Tanvier D, Dos Reis S, Gug F, Voisset C, Béringue V, Sabate R, Kikovska E, Talarek N, Bach S, Huang C, Desban N, Saupe SJ, Supattapone S, Thuret JY, Chédin S, Vilette D, Galons H, Sanyal S, Blondel M. Tribouillard-Tanvier D, et al. Among authors: blondel m. PLoS One. 2008 May 14;3(5):e2174. doi: 10.1371/journal.pone.0002174. PLoS One. 2008. PMID: 18478094 Free PMC article.
141 results