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Year Number of Results
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2007 1
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138 results

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Page 1
Toxicity and safety of rosemary (Rosmarinus officinalis): a comprehensive review.
Ghasemzadeh Rahbardar M, Hosseinzadeh H. Ghasemzadeh Rahbardar M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2025 Jan;398(1):9-23. doi: 10.1007/s00210-024-03336-9. Epub 2024 Aug 3. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39096378 Review.
RESULTS: The toxicological effects explored include affecting several organs such as the liver and kidney by causing atrophic and degenerative changes, increasing blood urea nitrogen (BUN), aspartate aminotransferase (AST), and reducing total serum pro …
RESULTS: The toxicological effects explored include affecting several organs such as the liver and kidney by causing atrophic and degenerati …
Association of blood urea nitrogen to creatinine ratio and long-term outcome among women with coronary artery bypass grafting surgery: filling gaps in female.
Zhang K, Zhang R, Li B, Cui D. Zhang K, et al. BMC Nephrol. 2025 Aug 7;26(1):443. doi: 10.1186/s12882-025-04283-0. BMC Nephrol. 2025. PMID: 40775690 Free PMC article.
BACKGROUND: The blood urea nitrogen to creatinine ratio (BUN/Cr) has been associated with poorer outcomes in various cardiovascular diseases, including acute and chronic heart failure (HF). ...A one unit increase in BUN/Cr was associated with lo …
BACKGROUND: The blood urea nitrogen to creatinine ratio (BUN/Cr) has been associated with poorer outcomes in var …
Trajectories of blood urea nitrogen and 28-day mortality in patients with sepsis-associated delirium: a retrospective cohort analysis of the MIMIC-IV database.
Zhao Y, Zhu H, Ding J, Qian L, Yao Z, Lu Q, Yang K. Zhao Y, et al. BMC Infect Dis. 2025 Oct 14;25(1):1326. doi: 10.1186/s12879-025-11600-3. BMC Infect Dis. 2025. PMID: 41087912 Free PMC article.
BACKGROUND: Blood urea nitrogen (BUN) levels had been reported to be Linked to the prognosis of critically ill patients. ...The BUN trajectories were classified into 4 classes: Class 1 exhibited stable normal BUN levels, with slight fluct …
BACKGROUND: Blood urea nitrogen (BUN) levels had been reported to be Linked to the prognosis of critically ill p …
Relationship between nitrogen loss and blood urea nitrogen concentrations in patients requiring continuous renal replacement therapy.
Sato T, Kushimoto S. Sato T, et al. Acute Med Surg. 2016 Aug 23;4(1):75-78. doi: 10.1002/ams2.219. eCollection 2017 Jan. Acute Med Surg. 2016. PMID: 29123839 Free PMC article.
AIM: It is well known that continuous renal replacement therapy (CRRT) produces some amount of nitrogen loss, but there are few tools that are easily applied to measure it. This study aimed to evaluate nitrogen loss using blood urea nitrogen ( …
AIM: It is well known that continuous renal replacement therapy (CRRT) produces some amount of nitrogen loss, but there are few tools …
Diagnostic utility of nasogastric tube aspiration and the ratio of blood urea nitrogen to creatinine for distinguishing upper and lower gastrointestinal tract bleeding.
Machlab S, García-Iglesias P, Martínez-Bauer E, Campo R, Calvet X, Brullet E. Machlab S, et al. Emergencias. 2018 Dic;30(6):419-423. Emergencias. 2018. PMID: 30638348 Free article. English, Spanish.
OBJECTIVES: The American College of Gastroenterology's 2016 clinical guidelines for treating lower gastrointestinal (GI) tract bleeding recommends evaluating of nasogastric tube aspiration and the ratio of blood urea nitrogen (BUN) to creatinine …
OBJECTIVES: The American College of Gastroenterology's 2016 clinical guidelines for treating lower gastrointestinal (GI) tract bleedi …
Bavachin ameliorates cisplatin-induced nephrotoxicity by enhancing mitochondrial β-oxidation and lipid metabolism through MFN2.
Luo S, Yang M, Jiang N, Li C, Liu Y, Sun L. Luo S, et al. Mol Med. 2025 Jun 11;31(1):234. doi: 10.1186/s10020-025-01283-6. Mol Med. 2025. PMID: 40500698 Free PMC article.
METHODS: C57/6L mice were randomly divided into control, DMSO, cisplatin, and cisplatin + Bavachin groups. Blood urea nitrogen (BUN), serum creatinine (SCr), reactive-oxygen-species (ROS), lipid accumulation, and apoptosis were assessed. ...RESULTS: Co …
METHODS: C57/6L mice were randomly divided into control, DMSO, cisplatin, and cisplatin + Bavachin groups. Blood urea nitro …
Method Comparison and Bias Estimation of Blood Urea Nitrogen (BUN), Creatinine (Cr), and Uric Acid (UA) Measurements between Two Analytical Methods.
Cai A, Qi S, Su Z, Yang Y, Shen H, Wang T, Dai Y. Cai A, et al. Clin Lab. 2017 Jan 1;63(1):73-77. doi: 10.7754/Clin.Lab.2016.160536. Clin Lab. 2017. PMID: 28164498
In this study, our aim is to compare the assay results of blood urea nitrogen (BUN), creatinine (Cr), and uric acid (UA) obtained through two distinct methods and then assess the analytical agreement of the two methods. METHODS: A test method (Vitros56 …
In this study, our aim is to compare the assay results of blood urea nitrogen (BUN), creatinine (Cr), and uric a …
Major reductions in unnecessary aspartate aminotransferase and blood urea nitrogen tests with a quality improvement initiative.
Strauss R, Cressman A, Cheung M, Weinerman A, Waldman S, Etchells E, Zahirieh A, Tartaro P, Rezmovitz J, Callum J. Strauss R, et al. BMJ Qual Saf. 2019 Oct;28(10):809-816. doi: 10.1136/bmjqs-2018-008991. Epub 2019 May 9. BMJ Qual Saf. 2019. PMID: 31073091
Aspartate aminotransferase (AST), commonly ordered with alanine aminotransferase (ALT) and blood urea nitrogen (BUN), commonly ordered with creatinine (Cr), often add little value to patient management at significant cost. ...IMPROVEMENTS: We created …
Aspartate aminotransferase (AST), commonly ordered with alanine aminotransferase (ALT) and blood urea nitrogen (BUN …
Prognostic value of blood urea nitrogen to albumin ratio in critically ill cirrhotic patients with ascites.
Duan Y, Sui W, Cai Z, Xia Y, Li J, Fu J. Duan Y, et al. Sci Rep. 2026 Feb 22;16(1):10164. doi: 10.1038/s41598-026-41107-z. Sci Rep. 2026. PMID: 41723285 Free PMC article.
Cirrhosis complicated by ascites is associated with high mortality in ICU settings, yet reliable prognostic biomarkers remain limited. While the blood urea nitrogen-to-albumin ratio (BAR) has been identified as a prognostic marker in various critical illnesse …
Cirrhosis complicated by ascites is associated with high mortality in ICU settings, yet reliable prognostic biomarkers remain limited. While …
Safety pharmacology--current and emerging concepts.
Hamdam J, Sethu S, Smith T, Alfirevic A, Alhaidari M, Atkinson J, Ayala M, Box H, Cross M, Delaunois A, Dermody A, Govindappa K, Guillon JM, Jenkins R, Kenna G, Lemmer B, Meecham K, Olayanju A, Pestel S, Rothfuss A, Sidaway J, Sison-Young R, Smith E, Stebbings R, Tingle Y, Valentin JP, Williams A, Williams D, Park K, Goldring C. Hamdam J, et al. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):229-41. doi: 10.1016/j.taap.2013.04.039. Epub 2013 Jun 1. Toxicol Appl Pharmacol. 2013. PMID: 23732082 Review.
SP studies are described in the International Conference on Harmonisation (ICH) S7A and S7B guidelines. The core battery and supplemental SP studies evaluate effects of a new chemical entity (NCE) at both anticipated therapeutic and supra-therapeutic exposures on major org …
SP studies are described in the International Conference on Harmonisation (ICH) S7A and S7B guidelines. The core battery and suppleme …
138 results