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Prognostic significance of concurrent gene mutations in intensively treated patients with IDH-mutated AML, an ALFA study.
Duchmann M, Micol JB, Duployez N, Raffoux E, Thomas X, Marolleau JP, Braun T, Adès L, Chantepie SP, Lemasle E, Berthon C, Malfuson JV, Pautas C, Lambert J, Boissel N, Celli-Lebras K, Caillot D, Turlure P, Vey N, Pigneux A, Récher C, Terré C, Gardin CJ, Itzykson RA, Preudhomme C, Dombret H, de Botton S. Duchmann M, et al. Blood. 2021 Feb 24:blood.2020010165. doi: 10.1182/blood.2020010165. Online ahead of print. Blood. 2021. PMID: 33881523
Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke.
Wang R, Zhu Y, Liu Z, Chang L, Bai X, Kang L, Cao Y, Yang X, Yu H, Shi MJ, Hu Y, Fan W, Zhao BQ. Wang R, et al. Blood. 2021 Feb 24:blood.2020008913. doi: 10.1182/blood.2020008913. Online ahead of print. Blood. 2021. PMID: 33881503
Peptidylarginine deiminase 4 (PAD4), a critical enzyme for NET formation, is also significantly upregulated in the ischemic brains in tPA-treated mice. Blood-brain barrier (BBB) disruption following ischemic challenge in an in vitro model of BBB was exacerbated after expos …
Peptidylarginine deiminase 4 (PAD4), a critical enzyme for NET formation, is also significantly upregulated in the ischemic brains in tPA-tr …