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Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia (AML).
Jetani H, Navarro-Bailón A, Maucher M, Frenz S, Verbruggen CM, Yeguas A, Vidriales MB, González M, Rial Saborido J, Kraus S, Mestermann K, Thomas S, Bonig H, Luu M, Monjezi R, Mougiakakos D, Sauer M, Einsele H, Hudecek M. Jetani H, et al. Blood. 2021 Jul 21:blood.2020009192. doi: 10.1182/blood.2020009192. Online ahead of print. Blood. 2021. PMID: 34289026
Phase I study of Ibrutinib and the CXCR4 antagonist Ulocuplumab in CXCR4 mutated Waldenstrom Macroglobulinemia.
Treon SP, Meid K, Hunter ZR, Flynn CA, Sarosiek SR, Leventoff CR, White TP, Cao Y, Roccaro AM, Sacco A, Demos MG, Guerrera ML, Kofides A, Liu X, Xu L, Patterson CJ, Munshi M, Tsakmaklis N, Yang G, Ghobrial IM, Branagan AR, Castillo JJ. Treon SP, et al. Blood. 2021 Jul 21:blood.2021012953. doi: 10.1182/blood.2021012953. Online ahead of print. Blood. 2021. PMID: 34289017
Prognostic value of minimal residual disease negativity in myeloma: combined analysis of POLLUX, CASTOR, ALCYONE, MAIA.
Cavo M, San-Miguel JFF, Usmani SZ, Weisel KC, Dimopoulos MAA, Avet-Loiseau H, Paiva B, Bahlis NJ, Plesner T, Hungria VTM, Moreau P, Mateos MV, Perrot A, Iida S, Facon T, Kumar SK, van de Donk NWCJ, Sonneveld P, Spencer A, Krevvata M, Heuck C, Wang J, Ukropec J, Kobos R, Sun S, Qi M, Munshi NC. Cavo M, et al. Blood. 2021 Jul 21:blood.2021011101. doi: 10.1182/blood.2021011101. Online ahead of print. Blood. 2021. PMID: 34289038