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982 results
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Deregulated degradation of the cdk inhibitor p27 and malignant transformation.
Bloom J, Pagano M. Bloom J, et al. Semin Cancer Biol. 2003 Feb;13(1):41-7. doi: 10.1016/s1044-579x(02)00098-6. Semin Cancer Biol. 2003. PMID: 12507555 Review.
Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase.
Bornstein G, Bloom J, Sitry-Shevah D, Nakayama K, Pagano M, Hershko A. Bornstein G, et al. Among authors: bloom j. J Biol Chem. 2003 Jul 11;278(28):25752-7. doi: 10.1074/jbc.M301774200. Epub 2003 May 2. J Biol Chem. 2003. PMID: 12730199
Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation.
Bloom J, Amador V, Bartolini F, DeMartino G, Pagano M. Bloom J, et al. Cell. 2003 Oct 3;115(1):71-82. doi: 10.1016/s0092-8674(03)00755-4. Cell. 2003. PMID: 14532004
An Rb-Skp2-p27 pathway mediates acute cell cycle inhibition by Rb and is retained in a partial-penetrance Rb mutant.
Ji P, Jiang H, Rekhtman K, Bloom J, Ichetovkin M, Pagano M, Zhu L. Ji P, et al. Among authors: bloom j. Mol Cell. 2004 Oct 8;16(1):47-58. doi: 10.1016/j.molcel.2004.09.029. Mol Cell. 2004. PMID: 15469821
To be or not to be ubiquitinated?
Bloom J, Pagano M. Bloom J, et al. Cell Cycle. 2004 Feb;3(2):138-40. Cell Cycle. 2004. PMID: 14712075 Review.
Butyrolactone: more than a kinase inhibitor?
Bloom J, Pagano M. Bloom J, et al. Cell Cycle. 2002 Mar-Apr;1(2):117-8. doi: 10.4161/cc.1.2.114. Cell Cycle. 2002. PMID: 12429918 Review. No abstract available.
Experimental tests to definitively determine ubiquitylation of a substrate.
Bloom J, Pagano M. Bloom J, et al. Methods Enzymol. 2005;399:249-66. doi: 10.1016/S0076-6879(05)99017-4. Methods Enzymol. 2005. PMID: 16338361
Novel role for Cdc14 sequestration: Cdc14 dephosphorylates factors that promote DNA replication.
Bloom J, Cross FR. Bloom J, et al. Mol Cell Biol. 2007 Feb;27(3):842-53. doi: 10.1128/MCB.01069-06. Epub 2006 Nov 20. Mol Cell Biol. 2007. PMID: 17116692 Free PMC article.
Multiple levels of cyclin specificity in cell-cycle control.
Bloom J, Cross FR. Bloom J, et al. Nat Rev Mol Cell Biol. 2007 Feb;8(2):149-60. doi: 10.1038/nrm2105. Nat Rev Mol Cell Biol. 2007. PMID: 17245415 Review.
Modification of Cul1 regulates its association with proteasomal subunits.
Bloom J, Peschiaroli A, Demartino G, Pagano M. Bloom J, et al. Cell Div. 2006 Apr 28;1:5. doi: 10.1186/1747-1028-1-5. Cell Div. 2006. PMID: 16759355 Free PMC article.
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