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Why highly expressed proteins evolve slowly.
Drummond DA, Bloom JD, Adami C, Wilke CO, Arnold FH. Drummond DA, et al. Among authors: bloom jd. Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14338-43. doi: 10.1073/pnas.0504070102. Epub 2005 Sep 21. Proc Natl Acad Sci U S A. 2005. PMID: 16176987 Free PMC article.
Protein stability promotes evolvability.
Bloom JD, Labthavikul ST, Otey CR, Arnold FH. Bloom JD, et al. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5869-74. doi: 10.1073/pnas.0510098103. Epub 2006 Mar 31. Proc Natl Acad Sci U S A. 2006. PMID: 16581913 Free PMC article.
Thermodynamic prediction of protein neutrality.
Bloom JD, Silberg JJ, Wilke CO, Drummond DA, Adami C, Arnold FH. Bloom JD, et al. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):606-11. doi: 10.1073/pnas.0406744102. Epub 2005 Jan 11. Proc Natl Acad Sci U S A. 2005. PMID: 15644440 Free PMC article.
412 results