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Ready, set, cleave: proteases in action.
Salpeter SJ, Blum G. Salpeter SJ, et al. Among authors: blum g. Chem Biol. 2013 Feb 21;20(2):137-8. doi: 10.1016/j.chembiol.2013.02.004. Chem Biol. 2013. PMID: 23438739
Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics.
Blum G, Gazit A, Levitzki A. Blum G, et al. J Biol Chem. 2003 Oct 17;278(42):40442-54. doi: 10.1074/jbc.M305490200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12869569
AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay (Blum, G., Gazit, A., and Levitzki, A. (2000) Biochemistry 39, 15705-15712). ...
AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay (Blum, …
Synthesis of a novel macrocyclic library: discovery of an IGF-1R inhibitor.
Qvit N, Reuveni H, Gazal S, Zundelevich A, Blum G, Niv MY, Feldstein A, Meushar S, Shalev DE, Friedler A, Gilon C. Qvit N, et al. Among authors: blum g. J Comb Chem. 2008 Mar-Apr;10(2):256-66. doi: 10.1021/cc700113c. Epub 2008 Feb 14. J Comb Chem. 2008. PMID: 18271560
Cathepsin B trafficking in thyroid carcinoma cells.
Tedelind S, Jordans S, Resemann H, Blum G, Bogyo M, Führer D, Brix K. Tedelind S, et al. Among authors: blum g. Thyroid Res. 2011 Aug 3;4 Suppl 1(Suppl 1):S2. doi: 10.1186/1756-6614-4-S1-S2. Thyroid Res. 2011. PMID: 21835049 Free PMC article.
Cysteine proteases in atherosclerosis.
Weiss-Sadan T, Gotsman I, Blum G. Weiss-Sadan T, et al. Among authors: blum g. FEBS J. 2017 May;284(10):1455-1472. doi: 10.1111/febs.14043. Epub 2017 Mar 9. FEBS J. 2017. PMID: 28207191 Review.
177 results