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Reward deficiency syndrome: a biogenetic model for the diagnosis and treatment of impulsive, addictive, and compulsive behaviors.
Blum K, Braverman ER, Holder JM, Lubar JF, Monastra VJ, Miller D, Lubar JO, Chen TJ, Comings DE. Blum K, et al. J Psychoactive Drugs. 2000 Nov;32 Suppl:i-iv, 1-112. doi: 10.1080/02791072.2000.10736099. J Psychoactive Drugs. 2000. PMID: 11280926 Review.
In order to explain the breakdown of the reward cascade due to both multiple genes and environmental stimuli (pleiotropism) and resultant aberrant behaviors, Blum united this hypodopaminergic trait under the rubric of a reward deficiency syndrome....
In order to explain the breakdown of the reward cascade due to both multiple genes and environmental stimuli (pleiotropism) and resultant ab …
Allelic association of the D2 dopamine receptor gene with cocaine dependence.
Noble EP, Blum K, Khalsa ME, Ritchie T, Montgomery A, Wood RC, Fitch RJ, Ozkaragoz T, Sheridan PJ, Anglin MD, et al. Noble EP, et al. Among authors: Blum K. Drug Alcohol Depend. 1993 Oct;33(3):271-85. doi: 10.1016/0376-8716(93)90113-5. Drug Alcohol Depend. 1993. PMID: 8261891
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