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Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau.
Brendel M, Deussing M, Blume T, Kaiser L, Probst F, Overhoff F, Peters F, von Ungern-Sternberg B, Ryazanov S, Leonov A, Griesinger C, Zwergal A, Levin J, Bartenstein P, Yakushev I, Cumming P, Boening G, Ziegler S, Herms J, Giese A, Rominger A. Brendel M, et al. Among authors: blume t. Alzheimers Res Ther. 2019 Aug 1;11(1):67. doi: 10.1186/s13195-019-0522-z. Alzheimers Res Ther. 2019. PMID: 31370885 Free PMC article.
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, Herms J, Haass C, Rominger A. Brendel M, et al. Among authors: blume t. Front Aging Neurosci. 2017 Jan 31;9:8. doi: 10.3389/fnagi.2017.00008. eCollection 2017. Front Aging Neurosci. 2017. PMID: 28197095 Free PMC article.
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
Brendel M, Focke C, Blume T, Peters F, Deussing M, Probst F, Jaworska A, Overhoff F, Albert N, Lindner S, von Ungern-Sternberg B, Bartenstein P, Haass C, Kleinberger G, Herms J, Rominger A. Brendel M, et al. Among authors: blume t. J Nucl Med. 2017 Dec;58(12):1984-1990. doi: 10.2967/jnumed.117.195107. Epub 2017 Jul 13. J Nucl Med. 2017. PMID: 28705919 Free article.
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification.
Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, Brendel M. Deussing M, et al. Among authors: blume t. Neuroimage. 2018 Jan 15;165:83-91. doi: 10.1016/j.neuroimage.2017.10.006. Epub 2017 Oct 5. Neuroimage. 2018. PMID: 28988133
Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium.
Deussing M, Blume T, Vomacka L, Mahler C, Focke C, Todica A, Unterrainer M, Albert NL, Lindner S, von Ungern-Sternberg B, Baumann K, Zwergal A, Bartenstein P, Herms J, Rominger A, Brendel M. Deussing M, et al. Among authors: blume t. Data Brief. 2018 May 5;19:331-336. doi: 10.1016/j.dib.2018.04.133. eCollection 2018 Aug. Data Brief. 2018. PMID: 29892655 Free PMC article.
Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology.
Brendel M, Yousefi BH, Blume T, Herz M, Focke C, Deussing M, Peters F, Lindner S, von Ungern-Sternberg B, Drzezga A, Bartenstein P, Haass C, Okamura N, Herms J, Yakushev I, Rominger A. Brendel M, et al. Among authors: blume t. Front Aging Neurosci. 2018 Jun 7;10:174. doi: 10.3389/fnagi.2018.00174. eCollection 2018. Front Aging Neurosci. 2018. PMID: 29930508 Free PMC article.
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.
Focke C, Blume T, Zott B, Shi Y, Deussing M, Peters F, Schmidt C, Kleinberger G, Lindner S, Gildehaus FJ, Beyer L, von Ungern-Sternberg B, Bartenstein P, Ozmen L, Baumann K, Dorostkar MM, Haass C, Adelsberger H, Herms J, Rominger A, Brendel M. Focke C, et al. Among authors: blume t. J Nucl Med. 2019 Apr;60(4):548-554. doi: 10.2967/jnumed.118.217703. Epub 2018 Sep 27. J Nucl Med. 2019. PMID: 30262517 Free article.
46 results