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Oncogenic kinase signalling.
Blume-Jensen P, Hunter T. Blume-Jensen P, et al. Nature. 2001 May 17;411(6835):355-65. doi: 10.1038/35077225. Nature. 2001. PMID: 11357143 Review.
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility.
Blume-Jensen P, Jiang G, Hyman R, Lee KF, O'Gorman S, Hunter T. Blume-Jensen P, et al. Nat Genet. 2000 Feb;24(2):157-62. doi: 10.1038/72814. Nat Genet. 2000. PMID: 10655061
The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136.
Blume-Jensen P, Janknecht R, Hunter T. Blume-Jensen P, et al. Curr Biol. 1998 Jun 18;8(13):779-82. doi: 10.1016/s0960-9822(98)70302-1. Curr Biol. 1998. PMID: 9651683
Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase.
Lu Z, Jiang G, Blume-Jensen P, Hunter T. Lu Z, et al. Mol Cell Biol. 2001 Jun;21(12):4016-31. doi: 10.1128/MCB.21.12.4016-4031.2001. Mol Cell Biol. 2001. PMID: 11359909 Free PMC article.
Kit/stem cell factor receptor-induced phosphatidylinositol 3'-kinase signalling is not required for normal development and function of interstitial cells of Cajal in mouse gastrointestinal tract.
Gibbons SJ, Rich A, Distad MA, Miller SM, Schmalz PF, Szurszewski JH, Sha L, Blume-Jensen P, Farrugia G. Gibbons SJ, et al. Neurogastroenterol Motil. 2003 Dec;15(6):643-53. doi: 10.1046/j.1350-1925.2003.00448.x. Neurogastroenterol Motil. 2003. PMID: 14651600
Two-dimensional phosphoamino acid analysis.
Blume-Jensen P, Hunter T. Blume-Jensen P, et al. Methods Mol Biol. 2001;124:49-65. doi: 10.1385/1-59259-059-4:49. Methods Mol Biol. 2001. PMID: 11100467 No abstract available.
Identification of the major phosphorylation sites for protein kinase C in kit/stem cell factor receptor in vitro and in intact cells.
Blume-Jensen P, Wernstedt C, Heldin CH, Rönnstrand L. Blume-Jensen P, et al. J Biol Chem. 1995 Jun 9;270(23):14192-200. doi: 10.1074/jbc.270.23.14192. J Biol Chem. 1995. PMID: 7539802
Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction.
Lennartsson J, Blume-Jensen P, Hermanson M, Pontén E, Carlberg M, Rönnstrand L. Lennartsson J, et al. Oncogene. 1999 Sep 30;18(40):5546-53. doi: 10.1038/sj.onc.1202929. Oncogene. 1999. PMID: 10523831
Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis.
Blume-Jensen P, Claesson-Welsh L, Siegbahn A, Zsebo KM, Westermark B, Heldin CH. Blume-Jensen P, et al. EMBO J. 1991 Dec;10(13):4121-8. EMBO J. 1991. PMID: 1721869 Free PMC article.
Modulation of Kit/stem cell factor receptor-induced signaling by protein kinase C.
Blume-Jensen P, Rönnstrand L, Gout I, Waterfield MD, Heldin CH. Blume-Jensen P, et al. J Biol Chem. 1994 Aug 26;269(34):21793-802. J Biol Chem. 1994. PMID: 7520444
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