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Human blood vessel organoids as a model of diabetic vasculopathy.
Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, Lindenhofer D, Chen G, Boehm M, Agu CA, Yang F, Fu B, Zuber J, Knoblich JA, Kerjaschki D, Penninger JM. Wimmer RA, et al. Among authors: Boehm M. Nature. 2019 Jan;565(7740):505-510. doi: 10.1038/s41586-018-0858-8. Epub 2019 Jan 16. Nature. 2019. PMID: 30651639
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease.
Zhou Q, Wang H, Schwartz DM, Stoffels M, Park YH, Zhang Y, Yang D, Demirkaya E, Takeuchi M, Tsai WL, Lyons JJ, Yu X, Ouyang C, Chen C, Chin DT, Zaal K, Chandrasekharappa SC, Hanson EP, Yu Z, Mullikin JC, Hasni SA, Wertz IE, Ombrello AK, Stone DL, Hoffmann P, Jones A, Barham BK, Leavis HL, van Royen-Kerkof A, Sibley C, Batu ED, Gül A, Siegel RM, Boehm M, Milner JD, Ozen S, Gadina M, Chae J, Laxer RM, Kastner DL, Aksentijevich I. Zhou Q, et al. Among authors: Boehm M. Nat Genet. 2016 Jan;48(1):67-73. doi: 10.1038/ng.3459. Epub 2015 Dec 7. Nat Genet. 2016. PMID: 26642243 Free PMC article. Clinical Trial.
Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability.
Evrard SM, Lecce L, Michelis KC, Nomura-Kitabayashi A, Pandey G, Purushothaman KR, d'Escamard V, Li JR, Hadri L, Fujitani K, Moreno PR, Benard L, Rimmele P, Cohain A, Mecham B, Randolph GJ, Nabel EG, Hajjar R, Fuster V, Boehm M, Kovacic JC. Evrard SM, et al. Among authors: Boehm M. Nat Commun. 2016 Jun 24;7:11853. doi: 10.1038/ncomms11853. Nat Commun. 2016. PMID: 27340017 Free PMC article.
CADASIL: new advances in basic science and clinical perspectives.
Ferrante EA, Cudrici CD, Boehm M. Ferrante EA, et al. Among authors: Boehm M. Curr Opin Hematol. 2019 May;26(3):193-198. doi: 10.1097/MOH.0000000000000497. Curr Opin Hematol. 2019. PMID: 30855338
VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism.
Wragg A, Mellad JA, Beltran LE, Konoplyannikov M, San H, Boozer S, Deans RJ, Mathur A, Lederman RJ, Kovacic JC, Boehm M. Wragg A, et al. Among authors: Boehm M. J Mol Med (Berl). 2008 Nov;86(11):1221-32. doi: 10.1007/s00109-008-0390-7. Epub 2008 Aug 9. J Mol Med (Berl). 2008. PMID: 18690419 Free PMC article.
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
Wood KC, Cortese-Krott MM, Kovacic JC, Noguchi A, Liu VB, Wang X, Raghavachari N, Boehm M, Kato GJ, Kelm M, Gladwin MT. Wood KC, et al. Among authors: Boehm M. Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1861-71. doi: 10.1161/ATVBAHA.112.301068. Epub 2013 May 23. Arterioscler Thromb Vasc Biol. 2013. PMID: 23702660 Free PMC article.
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