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Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion.
Lee DH, Dane MJ, van den Berg BM, Boels MG, van Teeffelen JW, de Mutsert R, den Heijer M, Rosendaal FR, van der Vlag J, van Zonneveld AJ, Vink H, Rabelink TJ; NEO study group. Lee DH, et al. Among authors: boels mg. PLoS One. 2014 May 9;9(5):e96477. doi: 10.1371/journal.pone.0096477. eCollection 2014. PLoS One. 2014. PMID: 24816787 Free PMC article.
A microscopic view on the renal endothelial glycocalyx.
Dane MJ, van den Berg BM, Lee DH, Boels MG, Tiemeier GL, Avramut MC, van Zonneveld AJ, van der Vlag J, Vink H, Rabelink TJ. Dane MJ, et al. Among authors: boels mg. Am J Physiol Renal Physiol. 2015 May 1;308(9):F956-66. doi: 10.1152/ajprenal.00532.2014. Epub 2015 Feb 11. Am J Physiol Renal Physiol. 2015. PMID: 25673809 Free article. Review.
Association of kidney function with changes in the endothelial surface layer.
Dane MJ, Khairoun M, Lee DH, van den Berg BM, Eskens BJ, Boels MG, van Teeffelen JW, Rops AL, van der Vlag J, van Zonneveld AJ, Reinders ME, Vink H, Rabelink TJ. Dane MJ, et al. Among authors: boels mg. Clin J Am Soc Nephrol. 2014 Apr;9(4):698-704. doi: 10.2215/CJN.08160813. Epub 2014 Jan 23. Clin J Am Soc Nephrol. 2014. PMID: 24458084 Free PMC article.
Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.
Boels MGS, Koudijs A, Avramut MC, Sol WMPJ, Wang G, van Oeveren-Rietdijk AM, van Zonneveld AJ, de Boer HC, van der Vlag J, van Kooten C, Eulberg D, van den Berg BM, IJpelaar DHT, Rabelink TJ. Boels MGS, et al. Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22. Am J Pathol. 2017. PMID: 28837800 Free article.
Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.
van den Berg BM, Wang G, Boels MGS, Avramut MC, Jansen E, Sol WMPJ, Lebrin F, van Zonneveld AJ, de Koning EJP, Vink H, Gröne HJ, Carmeliet P, van der Vlag J, Rabelink TJ. van den Berg BM, et al. Among authors: boels mgs. J Am Soc Nephrol. 2019 Oct;30(10):1886-1897. doi: 10.1681/ASN.2019020192. Epub 2019 Jul 15. J Am Soc Nephrol. 2019. PMID: 31308073 Free PMC article.
Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier.
Khalil R, Boels MGS; PALGA Group; van den Berg BM, Bruijn JA, Rabelink TJ, Hogendoorn PCW, Baelde HJ. Khalil R, et al. Among authors: boels mgs. Mol Genet Genomics. 2022 Mar;297(2):397-405. doi: 10.1007/s00438-022-01854-w. Epub 2022 Feb 1. Mol Genet Genomics. 2022. PMID: 35103870 Free PMC article.
Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions.
Thiem K, Hoeke G, Zhou E, Hijmans A, Houben T, Boels MG, Mol IM, Lutgens E, Shiri-Sverdlov R, Bussink J, Kanneganti TD, Boon MR, Stienstra R, Tack CJ, Rensen PC, Netea MG, Berbée JF, van Diepen JA. Thiem K, et al. Among authors: boels mg. Diab Vasc Dis Res. 2020 Jan-Feb;17(1):1479164119892140. doi: 10.1177/1479164119892140. Epub 2019 Dec 23. Diab Vasc Dis Res. 2020. PMID: 31868000 Free PMC article.