Boersma MD - Search Results

1

Evaluation of diverse α/β-backbone patterns for functional α-helix mimicry: analogues of the Bim BH3 domain.

Boersma MD, Haase HS, Peterson-Kaufman KJ, Lee EF, Clarke OB, Colman PM, Smith BJ, Horne WS, Fairlie WD, Gellman SH. Boersma MD, et al. J Am Chem Soc. 2012 Jan 11;134(1):315-23. doi: 10.1021/ja207148m. Epub 2011 Dec 8. J Am Chem Soc. 2012. PMID: 22040025 Free PMC article.

2

Sequence-based design of alpha/beta-peptide foldamers that mimic BH3 domains.

Horne WS, Boersma MD, Windsor MA, Gellman SH. Horne WS, et al. Among authors: boersma md. Angew Chem Int Ed Engl. 2008;47(15):2853-6. doi: 10.1002/anie.200705315. Angew Chem Int Ed Engl. 2008. PMID: 18330876 Free PMC article. No abstract available.

3

Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain.

Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Boersma MD, et al. Protein Sci. 2008 Jul;17(7):1232-40. doi: 10.1110/ps.032896.107. Epub 2008 May 8. Protein Sci. 2008. PMID: 18467496 Free PMC article.

4

Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures.

Hayouka Z, Chakraborty S, Liu R, Boersma MD, Weisblum B, Gellman SH. Hayouka Z, et al. Among authors: boersma md. J Am Chem Soc. 2013 Aug 14;135(32):11748-51. doi: 10.1021/ja406231b. Epub 2013 Aug 5. J Am Chem Soc. 2013. PMID: 23909610 Free PMC article.

5

Residue-Based Preorganization of BH3-Derived α/β-Peptides: Modulating Affinity, Selectivity and Proteolytic Susceptibility in α-Helix Mimics.

Peterson-Kaufman KJ, Haase HS, Boersma MD, Lee EF, Fairlie WD, Gellman SH. Peterson-Kaufman KJ, et al. Among authors: boersma md. ACS Chem Biol. 2015 Jul 17;10(7):1667-75. doi: 10.1021/acschembio.5b00109. Epub 2015 May 7. ACS Chem Biol. 2015. PMID: 25946900 Free PMC article.

6

A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin.

Cho PY, Joshi G, Boersma MD, Johnson JA, Murphy RM. Cho PY, et al. Among authors: boersma md. ACS Chem Neurosci. 2015 May 20;6(5):778-89. doi: 10.1021/cn500272a. Epub 2015 Mar 9. ACS Chem Neurosci. 2015. PMID: 25713928 Free PMC article.

7

Exo-mechanism proximity-accelerated alkylations: investigations of linkers, electrophiles and surface mutations in engineered cyclophilin-cyclosporin systems.

Levitsky K, Boersma MD, Ciolli CJ, Belshaw PJ. Levitsky K, et al. Among authors: boersma md. Chembiochem. 2005 May;6(5):890-9. doi: 10.1002/cbic.200400383. Chembiochem. 2005. PMID: 15832403

8

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.

Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ. Hebert AS, et al. Among authors: boersma md. Mol Cell. 2013 Jan 10;49(1):186-99. doi: 10.1016/j.molcel.2012.10.024. Epub 2012 Nov 29. Mol Cell. 2013. PMID: 23201123 Free PMC article.

9

Reader domain specificity and lysine demethylase-4 family function.

Su Z, Wang F, Lee JH, Stephens KE, Papazyan R, Voronina E, Krautkramer KA, Raman A, Thorpe JJ, Boersma MD, Kuznetsov VI, Miller MD, Taverna SD, Phillips GN Jr, Denu JM. Su Z, et al. Among authors: boersma md. Nat Commun. 2016 Nov 14;7:13387. doi: 10.1038/ncomms13387. Nat Commun. 2016. PMID: 27841353 Free PMC article.

10

Identifying Dysregulated Epigenetic Enzyme Activity in Castrate-Resistant Prostate Cancer Development.

Lee JH, Yang B, Lindahl AJ, Damaschke N, Boersma MD, Huang W, Corey E, Jarrard DF, Denu JM. Lee JH, et al. Among authors: boersma md. ACS Chem Biol. 2017 Nov 17;12(11):2804-2814. doi: 10.1021/acschembio.6b01035. Epub 2017 Oct 11. ACS Chem Biol. 2017. PMID: 28949514 Free PMC article.

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