Boersma YL - Search Results

1

DARPins and other repeat protein scaffolds: advances in engineering and applications.

Boersma YL, Plückthun A. Boersma YL, et al. Curr Opin Biotechnol. 2011 Dec;22(6):849-57. doi: 10.1016/j.copbio.2011.06.004. Epub 2011 Jun 27. Curr Opin Biotechnol. 2011. PMID: 21715155 Review.

2

High-Throughput Generation of Bispecific Binding Proteins by Sortase A-Mediated Coupling for Direct Functional Screening in Cell Culture.

Andres F, Schwill M, Boersma YL, Plückthun A. Andres F, et al. Among authors: boersma yl. Mol Cancer Ther. 2020 Apr;19(4):1080-1088. doi: 10.1158/1535-7163.MCT-19-0633. Epub 2019 Dec 23. Mol Cancer Ther. 2020. PMID: 31871271

3

Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling.

Boersma YL, Chao G, Steiner D, Wittrup KD, Plückthun A. Boersma YL, et al. J Biol Chem. 2011 Dec 2;286(48):41273-41285. doi: 10.1074/jbc.M111.293266. Epub 2011 Oct 6. J Biol Chem. 2011. PMID: 21979953 Free PMC article.

4

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.

Kiuchi T, Ortiz-Zapater E, Monypenny J, Matthews DR, Nguyen LK, Barbeau J, Coban O, Lawler K, Burford B, Rolfe DJ, de Rinaldis E, Dafou D, Simpson MA, Woodman N, Pinder S, Gillett CE, Devauges V, Poland SP, Fruhwirth G, Marra P, Boersma YL, Plückthun A, Gullick WJ, Yarden Y, Santis G, Winn M, Kholodenko BN, Martin-Fernandez ML, Parker P, Tutt A, Ameer-Beg SM, Ng T. Kiuchi T, et al. Among authors: boersma yl. Sci Signal. 2014 Aug 19;7(339):ra78. doi: 10.1126/scisignal.2005157. Sci Signal. 2014. PMID: 25140053

5

Advances in the Application of Designed Ankyrin Repeat Proteins (DARPins) as Research Tools and Protein Therapeutics.

Boersma YL. Boersma YL. Methods Mol Biol. 2018;1798:307-327. doi: 10.1007/978-1-4939-7893-9_23. Methods Mol Biol. 2018. PMID: 29868969 Review.

6

High-Throughput Screening in Protein Engineering: Recent Advances and Future Perspectives.

Wójcik M, Telzerow A, Quax WJ, Boersma YL. Wójcik M, et al. Among authors: boersma yl. Int J Mol Sci. 2015 Oct 20;16(10):24918-45. doi: 10.3390/ijms161024918. Int J Mol Sci. 2015. PMID: 26492240 Free PMC article. Review.

7

Selection strategies for improved biocatalysts.

Boersma YL, Dröge MJ, Quax WJ. Boersma YL, et al. FEBS J. 2007 May;274(9):2181-95. doi: 10.1111/j.1742-4658.2007.05782.x. FEBS J. 2007. PMID: 17448143 Free article. Review.

8

Engineering the specificity of Streptococcus pyogenes sortase A by loop grafting.

Wójcik M, Szala K, van Merkerk R, Quax WJ, Boersma YL. Wójcik M, et al. Among authors: boersma yl. Proteins. 2020 Nov;88(11):1394-1400. doi: 10.1002/prot.25958. Epub 2020 Jun 21. Proteins. 2020. PMID: 32501594 Free PMC article.

9

Sortase mutants with improved protein thermostability and enzymatic activity obtained by consensus design.

Wójcik M, Vázquez Torres S, Quax WJ, Boersma YL. Wójcik M, et al. Among authors: boersma yl. Protein Eng Des Sel. 2019 Dec 31;32(12):555-564. doi: 10.1093/protein/gzaa018. Protein Eng Des Sel. 2019. PMID: 32725168

10

Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection.

Dröge MJ, Boersma YL, van Pouderoyen G, Vrenken TE, Rüggeberg CJ, Reetz MT, Dijkstra BW, Quax WJ. Dröge MJ, et al. Among authors: boersma yl. Chembiochem. 2006 Jan;7(1):149-57. doi: 10.1002/cbic.200500308. Chembiochem. 2006. PMID: 16342303

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