Bogen S - Search Results

1

Characterization of resistance mutations against HCV ketoamide protease inhibitors.

Tong X, Bogen S, Chase R, Girijavallabhan V, Guo Z, Njoroge FG, Prongay A, Saksena A, Skelton A, Xia E, Ralston R. Tong X, et al. Among authors: bogen s. Antiviral Res. 2008 Mar;77(3):177-85. doi: 10.1016/j.antiviral.2007.11.010. Epub 2007 Dec 28. Antiviral Res. 2008. PMID: 18201776

2

In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.

Liu R, Abid K, Pichardo J, Pazienza V, Ingravallo P, Kong R, Agrawal S, Bogen S, Saksena A, Cheng KC, Prongay A, Njoroge FG, Baroudy BM, Negro F. Liu R, et al. Among authors: bogen s. J Antimicrob Chemother. 2007 Jan;59(1):51-8. doi: 10.1093/jac/dkl455. Epub 2006 Dec 5. J Antimicrob Chemother. 2007. PMID: 17151003

3

Correlation between PAMPA permeability and cellular activities of hepatitis C virus protease inhibitors.

Li C, Nair L, Liu T, Li F, Pichardo J, Agrawal S, Chase R, Tong X, Uss AS, Bogen S, Njoroge FG, Morrison RA, Cheng KC. Li C, et al. Among authors: bogen s. Biochem Pharmacol. 2008 Mar 1;75(5):1186-97. doi: 10.1016/j.bcp.2007.10.031. Epub 2007 Nov 7. Biochem Pharmacol. 2008. PMID: 18164692

4

Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease.

Venkatraman S, Velazquez F, Wu W, Blackman M, Chen KX, Bogen S, Nair L, Tong X, Chase R, Hart A, Agrawal S, Pichardo J, Prongay A, Cheng KC, Girijavallabhan V, Piwinski J, Shih NY, Njoroge FG. Venkatraman S, et al. Among authors: bogen s. J Med Chem. 2009 Jan 22;52(2):336-46. doi: 10.1021/jm800940u. J Med Chem. 2009. PMID: 19102654

5

Design, synthesis, and evaluation of oxygen-containing macrocyclic peptidomimetics as inhibitors of HCV NS3 protease.

Velázquez F, Venkatraman S, Blackman M, Pinto P, Bogen S, Sannigrahi M, Chen K, Pichardo J, Hart A, Tong X, Girijavallabhan V, Njoroge FG. Velázquez F, et al. Among authors: bogen s. J Med Chem. 2009 Feb 12;52(3):700-8. doi: 10.1021/jm801201u. J Med Chem. 2009. PMID: 19154150

6

Discovery of novel P3 sulfonamide-capped inhibitors of HCV NS3 protease. Inhibitors with improved cellular potencies.

Venkatraman S, Blackman M, Wu W, Nair L, Arasappan A, Padilla A, Bogen S, Bennett F, Chen K, Pichardo J, Tong X, Prongay A, Cheng KC, Girijavallabhan V, George Njoroge F. Venkatraman S, et al. Among authors: bogen s. Bioorg Med Chem. 2009 Jul 1;17(13):4486-95. doi: 10.1016/j.bmc.2009.05.012. Epub 2009 May 9. Bioorg Med Chem. 2009. PMID: 19481946

7

P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile.

Nair LG, Sannigrahi M, Bogen S, Pinto P, Chen KX, Prongay A, Tong X, Cheng KC, Girijavallabhan V, George Njoroge F. Nair LG, et al. Among authors: bogen s. Bioorg Med Chem Lett. 2010 Jan 15;20(2):567-70. doi: 10.1016/j.bmcl.2009.11.094. Epub 2009 Nov 22. Bioorg Med Chem Lett. 2010. PMID: 20004570

8

Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors.

Nair LG, Bogen S, Ruan S, Pan W, Pike R, Tong X, Cheng KC, Guo Z, Doll RJ, Njoroge FG. Nair LG, et al. Among authors: bogen s. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1689-92. doi: 10.1016/j.bmcl.2010.01.037. Epub 2010 Jan 20. Bioorg Med Chem Lett. 2010. PMID: 20149655

9

Computational Study of the Effects of Mutations A156T, D168V, and D168Q on the Binding of HCV Protease Inhibitors.

Guo Z, Prongay A, Tong X, Fischmann T, Bogen S, Velazquez F, Venkatraman S, Njoroge FG, Madison V. Guo Z, et al. Among authors: bogen s. J Chem Theory Comput. 2006 Nov;2(6):1657-63. doi: 10.1021/ct600151y. J Chem Theory Comput. 2006. PMID: 26627036

10

Depeptidization efforts on P3-P2' alpha-ketoamide inhibitors of HCV NS3-4A serine protease: effect on HCV replicon activity.

Bogen SL, Ruan S, Liu R, Agrawal S, Pichardo J, Prongay A, Baroudy B, Saksena AK, Girijavallabhan V, Njoroge FG. Bogen SL, et al. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1621-7. doi: 10.1016/j.bmcl.2005.12.013. Epub 2006 Jan 4. Bioorg Med Chem Lett. 2006. PMID: 16387495

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