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How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family.
Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ. Wallach D, et al. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S189-96. doi: 10.1186/ar585. Epub 2002 May 9. Arthritis Res. 2002. PMID: 12110139 Free PMC article. Review.
Tumor necrosis factor receptor and Fas signaling mechanisms.
Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP. Wallach D, et al. Annu Rev Immunol. 1999;17:331-67. doi: 10.1146/annurev.immunol.17.1.331. Annu Rev Immunol. 1999. PMID: 10358762 Review.
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1.
Malinin NL, Boldin MP, Kovalenko AV, Wallach D. Malinin NL, et al. Nature. 1997 Feb 6;385(6616):540-4. doi: 10.1038/385540a0. Nature. 1997. PMID: 9020361
A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other.
Varfolomeev EE, Boldin MP, Goncharov TM, Wallach D. Varfolomeev EE, et al. J Exp Med. 1996 Mar 1;183(3):1271-5. doi: 10.1084/jem.183.3.1271. J Exp Med. 1996. PMID: 8642271 Free PMC article.
Self-association of the "death domains" of the p55 tumor necrosis factor (TNF) receptor and Fas/APO1 prompts signaling for TNF and Fas/APO1 effects.
Boldin MP, Mett IL, Varfolomeev EE, Chumakov I, Shemer-Avni Y, Camonis JH, Wallach D. Boldin MP, et al. J Biol Chem. 1995 Jan 6;270(1):387-91. doi: 10.1074/jbc.270.1.387. J Biol Chem. 1995. PMID: 7529234
., Boldin, M., Varfolomeev, E. E., Bigda, Y., Camonis, H.J. and Mett, I. (1994) Cytokine 6, 556; Song, H.Y., Dunbar, J.D., and Bonner, D.B. (1994) J. ...
., Boldin, M., Varfolomeev, E. E., Bigda, Y., Camonis, H.J. and Mett, I. (1994) Cytokine 6, 556; Song, H.Y., Dunbar, J.D., and Bonner …
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