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Intrinsic determinants of neurotoxic aggregate formation by the amyloid beta peptide.
Brorsson AC, Bolognesi B, Tartaglia GG, Shammas SL, Favrin G, Watson I, Lomas DA, Chiti F, Vendruscolo M, Dobson CM, Crowther DC, Luheshi LM. Brorsson AC, et al. Among authors: bolognesi b. Biophys J. 2010 Apr 21;98(8):1677-84. doi: 10.1016/j.bpj.2009.12.4320. Biophys J. 2010. PMID: 20409489 Free PMC article.
Disulfide bonds reduce the toxicity of the amyloid fibrils formed by an extracellular protein.
Mossuto MF, Bolognesi B, Guixer B, Dhulesia A, Agostini F, Kumita JR, Tartaglia GG, Dumoulin M, Dobson CM, Salvatella X. Mossuto MF, et al. Among authors: bolognesi b. Angew Chem Int Ed Engl. 2011 Jul 25;50(31):7048-51. doi: 10.1002/anie.201100986. Epub 2011 Jun 10. Angew Chem Int Ed Engl. 2011. PMID: 21671315 Free PMC article. No abstract available.
Physicochemical principles of protein aggregation.
Bolognesi B, Tartaglia GG. Bolognesi B, et al. Prog Mol Biol Transl Sci. 2013;117:53-72. doi: 10.1016/B978-0-12-386931-9.00003-9. Prog Mol Biol Transl Sci. 2013. PMID: 23663965 Review.
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
Porcari R, Proukakis C, Waudby CA, Bolognesi B, Mangione PP, Paton JF, Mullin S, Cabrita LD, Penco A, Relini A, Verona G, Vendruscolo M, Stoppini M, Tartaglia GG, Camilloni C, Christodoulou J, Schapira AH, Bellotti V. Porcari R, et al. Among authors: bolognesi b. J Biol Chem. 2015 Jan 23;290(4):2395-404. doi: 10.1074/jbc.M114.610527. Epub 2014 Dec 10. J Biol Chem. 2015. PMID: 25505181 Free PMC article.
An Integrative Study of Protein-RNA Condensates Identifies Scaffolding RNAs and Reveals Players in Fragile X-Associated Tremor/Ataxia Syndrome.
Cid-Samper F, Gelabert-Baldrich M, Lang B, Lorenzo-Gotor N, Ponti RD, Severijnen LWFM, Bolognesi B, Gelpi E, Hukema RK, Botta-Orfila T, Tartaglia GG. Cid-Samper F, et al. Among authors: bolognesi b. Cell Rep. 2018 Dec 18;25(12):3422-3434.e7. doi: 10.1016/j.celrep.2018.11.076. Cell Rep. 2018. PMID: 30566867 Free PMC article.
27 results