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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
2000 1
2002 1
2003 1
2004 1
2008 1
2009 1
2010 3
2011 1
2012 3
2013 1
2015 1
2016 1
2018 1
2021 1
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18 results
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Page 1
Crystal structure of the human PRMT5:MEP50 complex.
Antonysamy S, Bonday Z, Campbell RM, Doyle B, Druzina Z, Gheyi T, Han B, Jungheim LN, Qian Y, Rauch C, Russell M, Sauder JM, Wasserman SR, Weichert K, Willard FS, Zhang A, Emtage S. Antonysamy S, et al. Among authors: bonday z. Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17960-5. doi: 10.1073/pnas.1209814109. Epub 2012 Oct 15. Proc Natl Acad Sci U S A. 2012. PMID: 23071334 Free PMC article.
LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.
Bonday ZQ, Cortez GS, Grogan MJ, Antonysamy S, Weichert K, Bocchinfuso WP, Li F, Kennedy S, Li B, Mader MM, Arrowsmith CH, Brown PJ, Eram MS, Szewczyk MM, Barsyte-Lovejoy D, Vedadi M, Guccione E, Campbell RM. Bonday ZQ, et al. ACS Med Chem Lett. 2018 Apr 23;9(7):612-617. doi: 10.1021/acsmedchemlett.8b00014. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034588 Free PMC article.
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.
Blanchard S, Soh CK, Lee CP, Poulsen A, Bonday Z, Goh KL, Goh KC, Goh MK, Pasha MK, Wang H, Williams M, Wood JM, Ethirajulu K, Dymock BW. Blanchard S, et al. Among authors: bonday z. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2880-4. doi: 10.1016/j.bmcl.2012.02.058. Epub 2012 Feb 27. Bioorg Med Chem Lett. 2012. PMID: 22437109
Antisense oligonucleotide-mediated MDM4 exon 6 skipping impairs tumor growth.
Dewaele M, Tabaglio T, Willekens K, Bezzi M, Teo SX, Low DH, Koh CM, Rambow F, Fiers M, Rogiers A, Radaelli E, Al-Haddawi M, Tan SY, Hermans E, Amant F, Yan H, Lakshmanan M, Koumar RC, Lim ST, Derheimer FA, Campbell RM, Bonday Z, Tergaonkar V, Shackleton M, Blattner C, Marine JC, Guccione E. Dewaele M, et al. Among authors: bonday z. J Clin Invest. 2016 Jan;126(1):68-84. doi: 10.1172/JCI82534. Epub 2015 Nov 23. J Clin Invest. 2016. PMID: 26595814 Free PMC article.
Structure-based design of Aurora A & B inhibitors.
Poulsen A, William A, Lee A, Blanchard S, Teo E, Deng W, Tu N, Tan E, Sun E, Goh KL, Ong WC, Ng CP, Goh KC, Bonday Z. Poulsen A, et al. Among authors: bonday z. J Comput Aided Mol Des. 2008 Dec;22(12):897-906. doi: 10.1007/s10822-008-9224-5. Epub 2008 Jun 24. J Comput Aided Mol Des. 2008. PMID: 18574696
Discovery of (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an orally active histone deacetylase inhibitor with a superior preclinical profile.
Wang H, Yu N, Chen D, Lee KC, Lye PL, Chang JW, Deng W, Ng MC, Lu T, Khoo ML, Poulsen A, Sangthongpitag K, Wu X, Hu C, Goh KC, Wang X, Fang L, Goh KL, Khng HH, Goh SK, Yeo P, Liu X, Bonday Z, Wood JM, Dymock BW, Kantharaj E, Sun ET. Wang H, et al. Among authors: bonday z. J Med Chem. 2011 Jul 14;54(13):4694-720. doi: 10.1021/jm2003552. Epub 2011 Jun 16. J Med Chem. 2011. PMID: 21634430
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