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Page 1
Arsenic trioxide: mechanisms of action.
Davison K, Mann KK, Miller WH Jr. Davison K, et al. Semin Hematol. 2002 Apr;39(2 Suppl 1):3-7. doi: 10.1053/shem.2002.33610. Semin Hematol. 2002. PMID: 12012315 Review.
The chimeric protein encoded by the PML-RAR alpha gene that is pathognomonic of acute promyelocytic leukemia (APL) causes the arrest of myeloid cell development at the promyelocyte stage, leading to an accumulation of abnormal promyelocytes in t …
The chimeric protein encoded by the PML-RAR alpha gene that is pathognomonic of acute promyelocytic leukemia (APL) causes the arre
Clinical implications of ELA2-, HAX1-, and G-CSF-receptor (CSF3R) mutations in severe congenital neutropenia.
Zeidler C, Germeshausen M, Klein C, Welte K. Zeidler C, et al. Br J Haematol. 2009 Feb;144(4):459-67. doi: 10.1111/j.1365-2141.2008.07425.x. Epub 2008 Dec 10. Br J Haematol. 2009. PMID: 19120359 Free article. Review.
Congenital Neutropenia (CN) is a heterogeneous bone marrow failure syndrome characterized by a maturation arrest of myelopoiesis at the level of the promyelocyte/myelocyte stage with peripheral blood absolute neutrophil counts below 0.5 x 10(9)/ …
Congenital Neutropenia (CN) is a heterogeneous bone marrow failure syndrome characterized by a maturation arrest of mye …
Rituximab associated late-onset neutropenia-a rheumatology case series and review of the literature.
Monaco WE, Jones JD, Rigby WF. Monaco WE, et al. Clin Rheumatol. 2016 Oct;35(10):2457-62. doi: 10.1007/s10067-016-3313-y. Epub 2016 May 21. Clin Rheumatol. 2016. PMID: 27209045 Review.
We determined the incidence of LON in patients with rheumatic disease at a single tertiary medical center, ascertained patient characteristics including results of bone marrow biopsies performed on four neutropenic patients, and performed a literature review. The in …
We determined the incidence of LON in patients with rheumatic disease at a single tertiary medical center, ascertained patient characteristi …
Molecular analysis of primitive hematopoietic cell proliferation control mechanisms.
Eaves CJ, Cashman JD, Sutherland HJ, Otsuka T, Humphries RK, Hogge DE, Lansdorp PL, Eaves AC. Eaves CJ, et al. Ann N Y Acad Sci. 1991;628:298-306. doi: 10.1111/j.1749-6632.1991.tb17260.x. Ann N Y Acad Sci. 1991. PMID: 1712556 Review.
Cells at two distinct early stages in the development of mature human blood cells from primitive totipotent hematopoietic stem cells can now be defined and quantitated by separate in vitro assays. Current evidence suggests that most, if not all, colony
Cells at two distinct early stages in the development of mature human blood cells from primitive totipotent hematopoiet
Mutant elastase in pathogenesis of cyclic and severe congenital neutropenia.
Aprikyan AA, Liles WC, Boxer LA, Dale DC. Aprikyan AA, et al. J Pediatr Hematol Oncol. 2002 Dec;24(9):784-6. doi: 10.1097/00043426-200212000-00025. J Pediatr Hematol Oncol. 2002. PMID: 12468929 Review.
Severe neutropenia is characterized by maturation arrest of myeloid cells at the promyelocyte stage of hematopoiesis. ...Short and long-term cultures of bone marrow CD34+ cells revealed reduced production of multipotent progenitors …
Severe neutropenia is characterized by maturation arrest of myeloid cells at the promyelocyte stage of hematopoi …