Bonnet S - Search Results

1

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension.

Sutendra G, Dromparis P, Bonnet S, Haromy A, McMurtry MS, Bleackley RC, Michelakis ED. Sutendra G, et al. Among authors: bonnet s. J Mol Med (Berl). 2011 Aug;89(8):771-83. doi: 10.1007/s00109-011-0762-2. Epub 2011 Aug 2. J Mol Med (Berl). 2011. PMID: 21809123

2

Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells.

Archer SL, Wu XC, Thébaud B, Nsair A, Bonnet S, Tyrrell B, McMurtry MS, Hashimoto K, Harry G, Michelakis ED. Archer SL, et al. Among authors: bonnet s. Circ Res. 2004 Aug 6;95(3):308-18. doi: 10.1161/01.RES.0000137173.42723.fb. Epub 2004 Jun 24. Circ Res. 2004. PMID: 15217912

3

Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.

McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED. McMurtry MS, et al. Among authors: bonnet s. Circ Res. 2004 Oct 15;95(8):830-40. doi: 10.1161/01.RES.0000145360.16770.9f. Epub 2004 Sep 16. Circ Res. 2004. PMID: 15375007

4

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.

McMurtry MS, Archer SL, Altieri DC, Bonnet S, Haromy A, Harry G, Bonnet S, Puttagunta L, Michelakis ED. McMurtry MS, et al. Among authors: bonnet s. J Clin Invest. 2005 Jun;115(6):1479-91. doi: 10.1172/JCI23203. J Clin Invest. 2005. PMID: 15931388 Free PMC article.

5

A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.

Archer SL, Michelakis ED, Thébaud B, Bonnet S, Moudgil R, Wu XC, Weir EK. Archer SL, et al. Among authors: bonnet s. Novartis Found Symp. 2006;272:157-71; discussion 171-5, 214-7. Novartis Found Symp. 2006. PMID: 16686435 Review.

6

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.

Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thébaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL. Bonnet S, et al. Circulation. 2006 Jun 6;113(22):2630-41. doi: 10.1161/CIRCULATIONAHA.105.609008. Epub 2006 May 30. Circulation. 2006. PMID: 16735674

7

Absence of malonyl coenzyme A decarboxylase in mice increases cardiac glucose oxidation and protects the heart from ischemic injury.

Dyck JR, Hopkins TA, Bonnet S, Michelakis ED, Young ME, Watanabe M, Kawase Y, Jishage K, Lopaschuk GD. Dyck JR, et al. Among authors: bonnet s. Circulation. 2006 Oct 17;114(16):1721-8. doi: 10.1161/CIRCULATIONAHA.106.642009. Epub 2006 Oct 9. Circulation. 2006. PMID: 17030679

8

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.

Bonnet S, Archer SL, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R, Lee CT, Lopaschuk GD, Puttagunta L, Bonnet S, Harry G, Hashimoto K, Porter CJ, Andrade MA, Thebaud B, Michelakis ED. Bonnet S, et al. Cancer Cell. 2007 Jan;11(1):37-51. doi: 10.1016/j.ccr.2006.10.020. Cancer Cell. 2007. PMID: 17222789 Free article.

9

Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.

Bonnet S, Archer SL. Bonnet S, et al. Pharmacol Ther. 2007 Jul;115(1):56-69. doi: 10.1016/j.pharmthera.2007.03.014. Epub 2007 Apr 21. Pharmacol Ther. 2007. PMID: 17583356 Review.

10

The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.

Bonnet S, Rochefort G, Sutendra G, Archer SL, Haromy A, Webster L, Hashimoto K, Bonnet SN, Michelakis ED. Bonnet S, et al. Among authors: bonnet sn. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11418-23. doi: 10.1073/pnas.0610467104. Epub 2007 Jun 27. Proc Natl Acad Sci U S A. 2007. PMID: 17596340 Free PMC article.

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