Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

121 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Brunet A, et al. Cell. 1999 Mar 19;96(6):857-68. doi: 10.1016/s0092-8674(00)80595-4. Cell. 1999. PMID: 10102273
Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/ threonine kinase Akt, which then phosphorylates and inactivates components of the apoptotic machinery, including BAD and Caspase 9. In this study, we demonstrate that Ak …
Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/ threonine kinase Akt, which t …
Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus.
Bonni A, Frank DA, Schindler C, Greenberg ME. Bonni A, et al. Science. 1993 Dec 3;262(5139):1575-9. doi: 10.1126/science.7504325. Science. 1993. PMID: 7504325
Components of a signaling pathway that couples the ciliary neurotrophic factor (CNTF) receptor to induction of transcription were identified. ...This DNA sequence, when inserted upstream of a reporter gene, conferred a transcriptional response to CNTF. A
Components of a signaling pathway that couples the ciliary neurotrophic factor (CNTF) receptor to induction of transcription were ide …
Interleukin 2 signaling involves the phosphorylation of Stat proteins.
Frank DA, Robertson MJ, Bonni A, Ritz J, Greenberg ME. Frank DA, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7779-83. doi: 10.1073/pnas.92.17.7779. Proc Natl Acad Sci U S A. 1995. PMID: 7544001 Free PMC article.
One of the most important cytokines involved in immune response regulation is interleukin 2 (IL-2), a potent activator of the proliferation and function of T lymphocytes and natural killer cells. ...These Stat proteins were found to translocate to the nucleus and to bind t …
One of the most important cytokines involved in immune response regulation is interleukin 2 (IL-2), a potent activator of the prolife …
Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals.
Bonni A, Ginty DD, Dudek H, Greenberg ME. Bonni A, et al. Mol Cell Neurosci. 1995 Apr;6(2):168-83. doi: 10.1006/mcne.1995.1015. Mol Cell Neurosci. 1995. PMID: 7551568
A mechanism has been characterized by which the transcription factor CREB regulates neurotrophin-induced gene expression. Whereas CREB can mediate calcium- or cyclic AMP-induced c-fos transcription independently of other promoter-bound transcription factors, CREB mediates
A mechanism has been characterized by which the transcription factor CREB regulates neurotrophin-induced gene expression. Whereas CRE
L-type voltage-sensitive Ca2+ channel activation regulates c-fos transcription at multiple levels.
Thompson MA, Ginty DD, Bonni A, Greenberg ME. Thompson MA, et al. J Biol Chem. 1995 Mar 3;270(9):4224-35. doi: 10.1074/jbc.270.9.4224. J Biol Chem. 1995. PMID: 7876182
A mechanism by which voltage-sensitive Ca2+ channel (VSCC) activation triggers c-fos transcription has been characterized. Ca2+ influx through VSCCs stimulates phosphorylation of the transcription factor cAMP response element-binding protein (CREB) on serine 133 leading to
A mechanism by which voltage-sensitive Ca2+ channel (VSCC) activation triggers c-fos transcription has been characterized. Ca2+ influ
L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway.
Misra RP, Bonni A, Miranti CK, Rivera VM, Sheng M, Greenberg ME. Misra RP, et al. J Biol Chem. 1994 Oct 14;269(41):25483-93. J Biol Chem. 1994. PMID: 7929249
A mechanism by which calcium-induced signals are transduced to the nucleus to activate transcription of the c-fos proto-oncogene has been characterized. ...Ca(2+)-induced SRF phosphorylation occurs via a pathway that may involve Ca2+/calmodulin-dependent kinases....
A mechanism by which calcium-induced signals are transduced to the nucleus to activate transcription of the c-fos proto-oncogene has
Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB.
Ginty DD, Bonni A, Greenberg ME. Ginty DD, et al. Cell. 1994 Jun 3;77(5):713-25. doi: 10.1016/0092-8674(94)90055-8. Cell. 1994. PMID: 8205620
A mechanism by which the nerve growth factor (NGF) signal is transduced to the nucleus to induce gene expression has been characterized. ...These findings suggest that CREB has a more widespread function than previously believed and functions in the nucleus as a
A mechanism by which the nerve growth factor (NGF) signal is transduced to the nucleus to induce gene expression has been characteriz
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway.
Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, Stahl N, Yancopoulos GD, Greenberg ME. Bonni A, et al. Science. 1997 Oct 17;278(5337):477-83. doi: 10.1126/science.278.5337.477. Science. 1997. PMID: 9334309
Activation of the CNTF receptor promoted differentiation of cerebral cortical precursor cells into astrocytes and inhibited differentiation of cortical precursors along a neuronal lineage. ...These findings suggest that cytokine activation of the JAK-STAT signaling pathway …
Activation of the CNTF receptor promoted differentiation of cerebral cortical precursor cells into astrocytes and inhibited differentiation …
Neurotrophin regulation of gene expression.
Bonni A, Greenberg ME. Bonni A, et al. Can J Neurol Sci. 1997 Nov;24(4):272-83. doi: 10.1017/s0317167100032935. Can J Neurol Sci. 1997. PMID: 9398973 Review.
The neurotrophins comprise a family of secreted proteins that elicit profound responses in cells of the developing and mature vertebrate nervous system including the regulation of neuronal survival and differentiation. ...Once activated, neurotrophin receptors trigger a
The neurotrophins comprise a family of secreted proteins that elicit profound responses in cells of the developing and mature vertebr …
Neuronal activity-dependent cell survival mediated by transcription factor MEF2.
Mao Z, Bonni A, Xia F, Nadal-Vicens M, Greenberg ME. Mao Z, et al. Science. 1999 Oct 22;286(5440):785-90. doi: 10.1126/science.286.5440.785. Science. 1999. PMID: 10531066
A transcription-dependent mechanism was identified by which calcium influx into neurons promoted cell survival. The transcription factor MEF2 was selectively expressed in newly generated postmitotic neurons and was required for the survival of these neurons. ...These findi
A transcription-dependent mechanism was identified by which calcium influx into neurons promoted cell survival. The transcription fac
121 results
Jump to page
Feedback