Augmenting glycosylation-directed folding pathways enhances the fidelity of HIV Env immunogen production in plants.
Margolin E, Allen JD, Verbeek M, Chapman R, Meyers A, van Diepen M, Ximba P, Motlou T, Moore PL, Woodward J, Strasser R, Crispin M, Williamson AL, Rybicki EP.
Margolin E, et al.
Biotechnol Bioeng. 2022 Oct;119(10):2919-2937. doi: 10.1002/bit.28169. Epub 2022 Jul 19.
Biotechnol Bioeng. 2022.
PMID: 35781691
Free PMC article.
Immunized rabbits developed comparable immune responses to the plant-produced and mammalian cell-derived antigens, including the induction of autologous neutralizing antibodies when the proteins were used to boost DNA and modified vaccinia Ankara virus …
Immunized rabbits developed comparable immune responses to the plant-produced and mammalian cell-derived antigens, incl …