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A loss of viral replicative capacity correlates with altered DNA polymerization kinetics by the human immunodeficiency virus reverse transcriptase bearing the K65R and L74V dideoxynucleoside resistance substitutions.
Deval J, Navarro JM, Selmi B, Courcambeck J, Boretto J, Halfon P, Garrido-Urbani S, Sire J, Canard B. Deval J, et al. Among authors: boretto j. J Biol Chem. 2004 Jun 11;279(24):25489-96. doi: 10.1074/jbc.M313534200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15044478 Free article.
The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
Selmi B, Deval J, Alvarez K, Boretto J, Sarfati S, Guerreiro C, Canard B. Selmi B, et al. Among authors: boretto j. J Biol Chem. 2003 Oct 17;278(42):40464-72. doi: 10.1074/jbc.M302928200. Epub 2003 Aug 5. J Biol Chem. 2003. PMID: 12902345 Free article.
129 results