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mRNA transcript distribution bias between Borrelia burgdorferi bacteria and their outer membrane vesicles.
Malge A, Ghai V, Reddy PJ, Baxter D, Kim TK, Moritz RL, Wang K. Malge A, et al. FEMS Microbiol Lett. 2018 Jul 1;365(13):fny135. doi: 10.1093/femsle/fny135. FEMS Microbiol Lett. 2018. PMID: 29846577 Free PMC article.
Borrelia burgdorferi, a bacterium in the spirochete phylum, is the causative agent of Lyme disease. Borrelia burgdorferi has a linear chromosome with a number of circular and linear plasmids. Bacteria, including B. burgdorferi, release spherical outer membrane ve
Borrelia burgdorferi, a bacterium in the spirochete phylum, is the causative agent of Lyme disease. Borrelia burgdorferi has a
Protein Secretion in Spirochetes.
Zückert WR. Zückert WR. Microbiol Spectr. 2019 May;7(3):10.1128/microbiolspec.PSIB-0026-2019. doi: 10.1128/microbiolspec.PSIB-0026-2019. Microbiol Spectr. 2019. PMID: 31198130 Free PMC article.
Treponema and Borrelia outer membranes lack lipopolysaccharide, with treponemes expressing only a few outer membrane proteins and Borrelia displaying a dizzying diversity of abundant surface lipoproteins instead. ...Proteins can be released from cells in outer membr …
Treponema and Borrelia outer membranes lack lipopolysaccharide, with treponemes expressing only a few outer membrane proteins and …
SNX3 drives maturation of Borrelia phagosomes by forming a hub for PI(3)P, Rab5a, and galectin-9.
Klose M, Salloum JE, Gonschior H, Linder S. Klose M, et al. J Cell Biol. 2019 Sep 2;218(9):3039-3059. doi: 10.1083/jcb.201812106. Epub 2019 Jul 23. J Cell Biol. 2019. PMID: 31337623 Free PMC article.
We show that the sorting nexin SNX3 is transported with Rab5a vesicles and that its PX domain enables vesicle-phagosome contact by binding to PI(3)P in the phagosomal coat. ...SNX3 thus forms a hub for two distinct vesicle populations, constituting a converge …
We show that the sorting nexin SNX3 is transported with Rab5a vesicles and that its PX domain enables vesicle-phagosome contac …
Extracellular HtrA serine proteases: An emerging new strategy in bacterial pathogenesis.
Backert S, Bernegger S, Skórko-Glonek J, Wessler S. Backert S, et al. Cell Microbiol. 2018 Jun;20(6):e12845. doi: 10.1111/cmi.12845. Epub 2018 Apr 30. Cell Microbiol. 2018. PMID: 29582532 Review.
Most of our knowledge on the function of exported HtrAs stems from research on Helicobacter pylori, Campylobacter jejuni, Borrelia burgdorferi, Bacillus anthracis, and Chlamydia species. ...
Most of our knowledge on the function of exported HtrAs stems from research on Helicobacter pylori, Campylobacter jejuni, Borrelia bu …
Spontaneously released Neisseria meningitidis outer membrane vesicles as vaccine platform: production and purification.
Gerritzen MJH, Salverda MLM, Martens DE, Wijffels RH, Stork M. Gerritzen MJH, et al. Vaccine. 2019 Nov 8;37(47):6978-6986. doi: 10.1016/j.vaccine.2019.01.076. Epub 2019 Aug 2. Vaccine. 2019. PMID: 31383485 Free article.
Outer membrane vesicles (OMVs) are nanoparticles produced by Gram-negative bacteria that can be used as vaccines. The application of OMVs as vaccine component can be expanded by expressing heterologous antigens on OMVs, creating an OMV-based antigen presenting platform. .. …
Outer membrane vesicles (OMVs) are nanoparticles produced by Gram-negative bacteria that can be used as vaccines. The application of …
Lipid exchange between Borrelia burgdorferi and host cells.
Crowley JT, Toledo AM, LaRocca TJ, Coleman JL, London E, Benach JL. Crowley JT, et al. PLoS Pathog. 2013 Jan;9(1):e1003109. doi: 10.1371/journal.ppat.1003109. Epub 2013 Jan 10. PLoS Pathog. 2013. PMID: 23326230 Free PMC article.
Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids that are essential for bacterial fitness, are antigenic, and could be important in mediating interactions with cells of the eukaryotic host. ...The transfer occurs through two diff
Borrelia burgdorferi, the agent of Lyme disease, has cholesterol and cholesterol-glycolipids that are essential for bacterial fitness
ER-Coordinated Activities of Rab22a and Rab5a Drive Phagosomal Compaction and Intracellular Processing of Borrelia burgdorferi by Macrophages.
Naj X, Linder S. Naj X, et al. Cell Rep. 2015 Sep 22;12(11):1816-30. doi: 10.1016/j.celrep.2015.08.027. Epub 2015 Sep 3. Cell Rep. 2015. PMID: 26344766 Free article.
Macrophages and dendritic cells counteract Borrelia dissemination through internalization and degradation of spirochetes. We now show that Borrelia internalization by primary human macrophages involves uptake and compaction into Rab22a-positive phagosomes that are i …
Macrophages and dendritic cells counteract Borrelia dissemination through internalization and degradation of spirochetes. We now show …
The flat-ribbon configuration of the periplasmic flagella of Borrelia burgdorferi and its relationship to motility and morphology.
Charon NW, Goldstein SF, Marko M, Hsieh C, Gebhardt LL, Motaleb MA, Wolgemuth CW, Limberger RJ, Rowe N. Charon NW, et al. J Bacteriol. 2009 Jan;191(2):600-7. doi: 10.1128/JB.01288-08. Epub 2008 Nov 14. J Bacteriol. 2009. PMID: 19011030 Free PMC article.
Electron cryotomography was used to analyze the structure of the Lyme disease spirochete, Borrelia burgdorferi. This methodology offers a new means for studying the native architecture of bacteria by eliminating the chemical fixing, dehydration, and staining steps of conve …
Electron cryotomography was used to analyze the structure of the Lyme disease spirochete, Borrelia burgdorferi. This methodology offe …
Specific adherence of Borrelia burgdorferi extracellular vesicles to human endothelial cells in culture.
Shoberg RJ, Thomas DD. Shoberg RJ, et al. Infect Immun. 1993 Sep;61(9):3892-900. Infect Immun. 1993. PMID: 8359911 Free PMC article.
Borrelia burgdorferi produces extracellular vesicles which contain some of the outer surface proteins of the bacterium (e.g., OspA and OspB). ...Quantitative experiments examining inhibition of B. burgdorferi-HUVE association as a function of prior vesicle-HU
Borrelia burgdorferi produces extracellular vesicles which contain some of the outer surface proteins of the bacterium (e.g.,
The enolase of Borrelia burgdorferi is a plasminogen receptor released in outer membrane vesicles.
Toledo A, Coleman JL, Kuhlow CJ, Crowley JT, Benach JL. Toledo A, et al. Infect Immun. 2012 Jan;80(1):359-68. doi: 10.1128/IAI.05836-11. Epub 2011 Nov 14. Infect Immun. 2012. PMID: 22083700 Free PMC article.
The agent of Lyme disease, Borrelia burgdorferi, has a number of outer membrane proteins that are differentially regulated during its life cycle. ...In borreliae, as well as in other bacteria, a number of membrane proteins have been implicated in binding plasminogen …
The agent of Lyme disease, Borrelia burgdorferi, has a number of outer membrane proteins that are differentially regulated during its …
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