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Insights into the structure of class B GPCRs.
Hollenstein K, de Graaf C, Bortolato A, Wang MW, Marshall FH, Stevens RC. Hollenstein K, et al. Among authors: bortolato a. Trends Pharmacol Sci. 2014 Jan;35(1):12-22. doi: 10.1016/j.tips.2013.11.001. Epub 2013 Dec 18. Trends Pharmacol Sci. 2014. PMID: 24359917 Free PMC article. Review.
Structure of Class B GPCRs: new horizons for drug discovery.
Bortolato A, Doré AS, Hollenstein K, Tehan BG, Mason JS, Marshall FH. Bortolato A, et al. Br J Pharmacol. 2014 Jul;171(13):3132-45. doi: 10.1111/bph.12689. Br J Pharmacol. 2014. PMID: 24628305 Free PMC article. Review.
Generic GPCR residue numbers - aligning topology maps while minding the gaps.
Isberg V, de Graaf C, Bortolato A, Cherezov V, Katritch V, Marshall FH, Mordalski S, Pin JP, Stevens RC, Vriend G, Gloriam DE. Isberg V, et al. Among authors: bortolato a. Trends Pharmacol Sci. 2015 Jan;36(1):22-31. doi: 10.1016/j.tips.2014.11.001. Epub 2014 Dec 22. Trends Pharmacol Sci. 2015. PMID: 25541108 Free PMC article. Review.
Structure of class B GPCR corticotropin-releasing factor receptor 1.
Hollenstein K, Kean J, Bortolato A, Cheng RK, Doré AS, Jazayeri A, Cooke RM, Weir M, Marshall FH. Hollenstein K, et al. Among authors: bortolato a. Nature. 2013 Jul 25;499(7459):438-43. doi: 10.1038/nature12357. Epub 2013 Jul 17. Nature. 2013. PMID: 23863939
Extra-helical binding site of a glucagon receptor antagonist.
Jazayeri A, Doré AS, Lamb D, Krishnamurthy H, Southall SM, Baig AH, Bortolato A, Koglin M, Robertson NJ, Errey JC, Andrews SP, Teobald I, Brown AJ, Cooke RM, Weir M, Marshall FH. Jazayeri A, et al. Among authors: bortolato a. Nature. 2016 May 12;533(7602):274-7. doi: 10.1038/nature17414. Epub 2016 Apr 25. Nature. 2016. PMID: 27111510
Crystal structure of the GLP-1 receptor bound to a peptide agonist.
Jazayeri A, Rappas M, Brown AJH, Kean J, Errey JC, Robertson NJ, Fiez-Vandal C, Andrews SP, Congreve M, Bortolato A, Mason JS, Baig AH, Teobald I, Doré AS, Weir M, Cooke RM, Marshall FH. Jazayeri A, et al. Among authors: bortolato a. Nature. 2017 Jun 8;546(7657):254-258. doi: 10.1038/nature22800. Epub 2017 May 31. Nature. 2017. PMID: 28562585
52 results