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Regulating Rap small G-proteins in time and space.
Gloerich M, Bos JL. Gloerich M, et al. Among authors: bos jl. Trends Cell Biol. 2011 Oct;21(10):615-23. doi: 10.1016/j.tcb.2011.07.001. Epub 2011 Aug 4. Trends Cell Biol. 2011. PMID: 21820312 Review.
Rap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation.
Post A, Pannekoek WJ, Ponsioen B, Vliem MJ, Bos JL. Post A, et al. Among authors: bos jl. Mol Cell Biol. 2015 Jul;35(14):2495-502. doi: 10.1128/MCB.01453-14. Epub 2015 May 11. Mol Cell Biol. 2015. PMID: 25963656 Free PMC article.
Dynamic interaction of cAMP with the Rap guanine-nucleotide exchange factor Epac1.
Kraemer A, Rehmann HR, Cool RH, Theiss C, de Rooij J, Bos JL, Wittinghofer A. Kraemer A, et al. Among authors: bos jl. J Mol Biol. 2001 Mar 9;306(5):1167-77. doi: 10.1006/jmbi.2001.4444. J Mol Biol. 2001. PMID: 11237625
Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrity.
Pellis-van Berkel W, Verheijen MH, Cuppen E, Asahina M, de Rooij J, Jansen G, Plasterk RH, Bos JL, Zwartkruis FJ. Pellis-van Berkel W, et al. Among authors: bos jl. Mol Biol Cell. 2005 Jan;16(1):106-16. doi: 10.1091/mbc.e04-06-0492. Epub 2004 Nov 3. Mol Biol Cell. 2005. PMID: 15525675 Free PMC article.
Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection.
Amsen D, Kruisbeek A, Bos JL, Reedquist K. Amsen D, et al. Among authors: bos jl. Eur J Immunol. 2000 Oct;30(10):2832-41. doi: 10.1002/1521-4141(200010)30:10<2832::AID-IMMU2832>3.0.CO;2-D. Eur J Immunol. 2000. PMID: 11069064
Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs.
de Rooij J, Rehmann H, van Triest M, Cool RH, Wittinghofer A, Bos JL. de Rooij J, et al. Among authors: bos jl. J Biol Chem. 2000 Jul 7;275(27):20829-36. doi: 10.1074/jbc.M001113200. J Biol Chem. 2000. PMID: 10777494
PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2.
de Rooij J, Boenink NM, van Triest M, Cool RH, Wittinghofer A, Bos JL. de Rooij J, et al. Among authors: bos jl. J Biol Chem. 1999 Dec 31;274(53):38125-30. doi: 10.1074/jbc.274.53.38125. J Biol Chem. 1999. PMID: 10608883
RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral.
de Bruyn KM, de Rooij J, Wolthuis RM, Rehmann H, Wesenbeek J, Cool RH, Wittinghofer AH, Bos JL. de Bruyn KM, et al. Among authors: bos jl. J Biol Chem. 2000 Sep 22;275(38):29761-6. doi: 10.1074/jbc.M001160200. J Biol Chem. 2000. PMID: 10889189
Sequential regulation of the small GTPase Rap1 in human platelets.
Franke B, van Triest M, de Bruijn KM, van Willigen G, Nieuwenhuis HK, Negrier C, Akkerman JW, Bos JL. Franke B, et al. Among authors: bos jl. Mol Cell Biol. 2000 Feb;20(3):779-85. doi: 10.1128/mcb.20.3.779-785.2000. Mol Cell Biol. 2000. PMID: 10629034 Free PMC article.
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