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Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation.
Mazzo F, Butnaru I, Grubisha O, Ficulle E, Sanger H, Fitzgerald G, Pan F, Pasqui F, Murray T, Monn J, Li X, Hutton M, Bose S, Schiavo G, Sher E. Mazzo F, et al. Among authors: bose s. J Pharmacol Exp Ther. 2022 Nov;383(2):117-128. doi: 10.1124/jpet.122.001307. Epub 2022 Sep 18. J Pharmacol Exp Ther. 2022. PMID: 36116796
Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia.
Chan WY, McKinzie DL, Bose S, Mitchell SN, Witkin JM, Thompson RC, Christopoulos A, Lazareno S, Birdsall NJ, Bymaster FP, Felder CC. Chan WY, et al. Among authors: bose s. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10978-83. doi: 10.1073/pnas.0800567105. Epub 2008 Aug 4. Proc Natl Acad Sci U S A. 2008. PMID: 18678919 Free PMC article.
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Wang H, Li Y, Ryder JW, Hole JT, Ebert PJ, Airey DC, Qian HR, Logsdon B, Fisher A, Ahmed Z, Murray TK, Cavallini A, Bose S, Eastwood BJ, Collier DA, Dage JL, Miller BB, Merchant KM, O'Neill MJ, Demattos RB. Wang H, et al. Among authors: bose s. Mol Neurodegener. 2018 Dec 17;13(1):65. doi: 10.1186/s13024-018-0296-y. Mol Neurodegener. 2018. PMID: 30558641 Free PMC article.
An unbiased approach to identifying tau kinases that phosphorylate tau at sites associated with Alzheimer disease.
Cavallini A, Brewerton S, Bell A, Sargent S, Glover S, Hardy C, Moore R, Calley J, Ramachandran D, Poidinger M, Karran E, Davies P, Hutton M, Szekeres P, Bose S. Cavallini A, et al. Among authors: bose s. J Biol Chem. 2013 Aug 9;288(32):23331-47. doi: 10.1074/jbc.M113.463984. Epub 2013 Jun 24. J Biol Chem. 2013. PMID: 23798682 Free PMC article.
A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity.
Ahmed Z, Cooper J, Murray TK, Garn K, McNaughton E, Clarke H, Parhizkar S, Ward MA, Cavallini A, Jackson S, Bose S, Clavaguera F, Tolnay M, Lavenir I, Goedert M, Hutton ML, O'Neill MJ. Ahmed Z, et al. Among authors: bose s. Acta Neuropathol. 2014 May;127(5):667-83. doi: 10.1007/s00401-014-1254-6. Epub 2014 Feb 16. Acta Neuropathol. 2014. PMID: 24531916 Free PMC article.
Conformation determines the seeding potencies of native and recombinant Tau aggregates.
Falcon B, Cavallini A, Angers R, Glover S, Murray TK, Barnham L, Jackson S, O'Neill MJ, Isaacs AM, Hutton ML, Szekeres PG, Goedert M, Bose S. Falcon B, et al. Among authors: bose s. J Biol Chem. 2015 Jan 9;290(2):1049-65. doi: 10.1074/jbc.M114.589309. Epub 2014 Nov 18. J Biol Chem. 2015. PMID: 25406315 Free PMC article.
2,390 results