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Lung eQTLs to help reveal the molecular underpinnings of asthma.
Hao K, Bossé Y, Nickle DC, Paré PD, Postma DS, Laviolette M, Sandford A, Hackett TL, Daley D, Hogg JC, Elliott WM, Couture C, Lamontagne M, Brandsma CA, van den Berge M, Koppelman G, Reicin AS, Nicholson DW, Malkov V, Derry JM, Suver C, Tsou JA, Kulkarni A, Zhang C, Vessey R, Opiteck GJ, Curtis SP, Timens W, Sin DD. Hao K, et al. Among authors: bosse y. PLoS Genet. 2012;8(11):e1003029. doi: 10.1371/journal.pgen.1003029. Epub 2012 Nov 29. PLoS Genet. 2012. PMID: 23209423 Free PMC article.
Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
Thun GA, Imboden M, Ferrarotti I, Kumar A, Obeidat M, Zorzetto M, Haun M, Curjuric I, Couto Alves A, Jackson VE, Albrecht E, Ried JS, Teumer A, Lopez LM, Huffman JE, Enroth S, Bossé Y, Hao K, Timens W, Gyllensten U, Polasek O, Wilson JF, Rudan I, Hayward C, Sandford AJ, Deary IJ, Koch B, Reischl E, Schulz H, Hui J, James AL, Rochat T, Russi EW, Jarvelin MR, Strachan DP, Hall IP, Tobin MD, Dahl M, Fallgaard Nielsen S, Nordestgaard BG, Kronenberg F, Luisetti M, Probst-Hensch NM. Thun GA, et al. Among authors: bosse y. PLoS Genet. 2013;9(8):e1003585. doi: 10.1371/journal.pgen.1003585. Epub 2013 Aug 22. PLoS Genet. 2013. PMID: 23990791 Free PMC article.
GSTCD and INTS12 regulation and expression in the human lung.
Obeidat M, Miller S, Probert K, Billington CK, Henry AP, Hodge E, Nelson CP, Stewart CE, Swan C, Wain LV, Soler Artigas M, Melén E, Ushey K, Hao K, Lamontagne M, Bossé Y, Postma DS, Tobin MD, Sayers I, Hall IP. Obeidat M, et al. Among authors: bosse y. PLoS One. 2013 Sep 18;8(9):e74630. doi: 10.1371/journal.pone.0074630. eCollection 2013. PLoS One. 2013. PMID: 24058608 Free PMC article.
Susceptibility to chronic mucus hypersecretion, a genome wide association study.
Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HS, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat M, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS; LifeLines Cohort study. Dijkstra AE, et al. Among authors: bosse y. PLoS One. 2014 Apr 8;9(4):e91621. doi: 10.1371/journal.pone.0091621. eCollection 2014. PLoS One. 2014. PMID: 24714607 Free PMC article.
Lung expression quantitative trait loci data set identifies important functional polymorphisms in the asthma-associated IL1RL1 region.
Akhabir L, Bérubé JC, Bossé Y, Laviolette M, Hao K, Nickle DC, Timens W, Sin DD, Paré PD, Postma DS, Sandford AJ. Akhabir L, et al. Among authors: bosse y. J Allergy Clin Immunol. 2014 Sep;134(3):729-31. doi: 10.1016/j.jaci.2014.02.039. Epub 2014 Apr 18. J Allergy Clin Immunol. 2014. PMID: 24746754 No abstract available.
Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.
Wain LV, Sayers I, Soler Artigas M, Portelli MA, Zeggini E, Obeidat M, Sin DD, Bossé Y, Nickle D, Brandsma CA, Malarstig A, Vangjeli C, Jelinsky SA, John S, Kilty I, McKeever T, Shrine NR, Cook JP, Patel S, Spector TD, Hollox EJ, Hall IP, Tobin MD. Wain LV, et al. Among authors: bosse y. PLoS Genet. 2014 May 1;10(5):e1004314. doi: 10.1371/journal.pgen.1004314. eCollection 2014 May. PLoS Genet. 2014. PMID: 24786987 Free PMC article.
349 results