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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM. Boström P, et al. Among authors: Bostrom EA. Nature. 2012 Jan 11;481(7382):463-8. doi: 10.1038/nature10777. Nature. 2012. PMID: 22237023 Free PMC article.
FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice.
Bosma M, Gerling M, Pasto J, Georgiadi A, Graham E, Shilkova O, Iwata Y, Almer S, Söderman J, Toftgård R, Wermeling F, Boström EA, Boström PA. Bosma M, et al. Among authors: Bostrom EA, Bostrom PA. Nat Commun. 2016 Apr 12;7:11314. doi: 10.1038/ncomms11314. Nat Commun. 2016. PMID: 27066907 Free PMC article.
Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines.
Boström EA, Kindstedt E, Sulniute R, Palmqvist P, Majster M, Holm CK, Zwicker S, Clark R, Önell S, Johansson I, Lerner UH, Lundberg P. Boström EA, et al. PLoS One. 2015 Aug 4;10(8):e0134608. doi: 10.1371/journal.pone.0134608. eCollection 2015. PLoS One. 2015. PMID: 26241961 Free PMC article.
Receptor-Type Protein-Tyrosine Phosphatase ζ and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1.
Zwicker S, Bureik D, Bosma M, Martinez GL, Almer S, Boström EA. Zwicker S, et al. Among authors: Bostrom EA. PLoS One. 2016 Nov 29;11(11):e0167324. doi: 10.1371/journal.pone.0167324. eCollection 2016. PLoS One. 2016. PMID: 27898738 Free PMC article.
Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200Rlow Monocyte-Derived Cells in Periodontitis.
Björnfot Holmström S, Clark R, Zwicker S, Bureik D, Kvedaraite E, Bernasconi E, Nguyen Hoang AT, Johannsen G, Marsland BJ, Boström EA, Svensson M. Björnfot Holmström S, et al. Among authors: Bostrom EA. J Immunol. 2017 Dec 15;199(12):4023-4035. doi: 10.4049/jimmunol.1700672. Epub 2017 Nov 3. J Immunol. 2017. PMID: 29101312
Interleukin 34: a new modulator of human and experimental inflammatory bowel disease.
Zwicker S, Martinez GL, Bosma M, Gerling M, Clark R, Majster M, Söderman J, Almer S, Boström EA. Zwicker S, et al. Among authors: Bostrom EA. Clin Sci (Lond). 2015 Aug;129(3):281-90. doi: 10.1042/CS20150176. Clin Sci (Lond). 2015. PMID: 25896238 Free PMC article.
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