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The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells.
Woldt E, Terrand J, Mlih M, Matz RL, Bruban V, Coudane F, Foppolo S, El Asmar Z, Chollet ME, Ninio E, Bednarczyk A, Thiersé D, Schaeffer C, Van Dorsselaer A, Boudier C, Wahli W, Chambon P, Metzger D, Herz J, Boucher P. Woldt E, et al. Among authors: boucher p. Nat Commun. 2012;3:1077. doi: 10.1038/ncomms2087. Nat Commun. 2012. PMID: 23011131 Free PMC article.
Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation.
El Asmar Z, Terrand J, Jenty M, Host L, Mlih M, Zerr A, Justiniano H, Matz RL, Boudier C, Scholler E, Garnier JM, Bertaccini D, Thiersé D, Schaeffer C, Van Dorsselaer A, Herz J, Bruban V, Boucher P. El Asmar Z, et al. Among authors: boucher p. J Biol Chem. 2016 Mar 4;291(10):5116-27. doi: 10.1074/jbc.M116.714485. Epub 2016 Jan 19. J Biol Chem. 2016. PMID: 26792864 Free PMC article.
atherosclerosis: gone with the Wnt?
Boucher P, Matz RL, Terrand J. Boucher P, et al. Atherosclerosis. 2020 May;301:15-22. doi: 10.1016/j.atherosclerosis.2020.03.024. Epub 2020 Apr 6. Atherosclerosis. 2020. PMID: 32289618 Free article. Review.
219 results