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42 results
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Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario.
Chipuk JE, Bouchier-Hayes L, Green DR. Chipuk JE, et al. Cell Death Differ. 2006 Aug;13(8):1396-402. doi: 10.1038/sj.cdd.4401963. Epub 2006 May 19. Cell Death Differ. 2006. PMID: 16710362 Review.
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.
Ichim G, Lopez J, Ahmed SU, Muthalagu N, Giampazolias E, Delgado ME, Haller M, Riley JS, Mason SM, Athineos D, Parsons MJ, van de Kooij B, Bouchier-Hayes L, Chalmers AJ, Rooswinkel RW, Oberst A, Blyth K, Rehm M, Murphy DJ, Tait SWG. Ichim G, et al. Mol Cell. 2015 Mar 5;57(5):860-872. doi: 10.1016/j.molcel.2015.01.018. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702873 Free PMC article.
A unified model of mammalian BCL-2 protein family interactions at the mitochondria.
Llambi F, Moldoveanu T, Tait SW, Bouchier-Hayes L, Temirov J, McCormick LL, Dillon CP, Green DR. Llambi F, et al. Mol Cell. 2011 Nov 18;44(4):517-31. doi: 10.1016/j.molcel.2011.10.001. Epub 2011 Oct 27. Mol Cell. 2011. PMID: 22036586 Free PMC article.
Live to dead cell imaging.
Tait SW, Bouchier-Hayes L, Oberst A, Connell S, Green DR. Tait SW, et al. Methods Mol Biol. 2009;559:33-48. doi: 10.1007/978-1-60327-017-5_3. Methods Mol Biol. 2009. PMID: 19609747
Caspase-2-induced apoptosis requires bid cleavage: a physiological role for bid in heat shock-induced death.
Bonzon C, Bouchier-Hayes L, Pagliari LJ, Green DR, Newmeyer DD. Bonzon C, et al. Mol Biol Cell. 2006 May;17(5):2150-7. doi: 10.1091/mbc.e05-12-1107. Epub 2006 Feb 22. Mol Biol Cell. 2006. PMID: 16495337 Free PMC article.
Mitochondria: pharmacological manipulation of cell death.
Bouchier-Hayes L, Lartigue L, Newmeyer DD. Bouchier-Hayes L, et al. J Clin Invest. 2005 Oct;115(10):2640-7. doi: 10.1172/JCI26274. J Clin Invest. 2005. PMID: 16200197 Free PMC article. Review.
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
Chipuk JE, Bouchier-Hayes L, Kuwana T, Newmeyer DD, Green DR. Chipuk JE, et al. Science. 2005 Sep 9;309(5741):1732-5. doi: 10.1126/science.1114297. Science. 2005. PMID: 16151013
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, Green DR. Chipuk JE, et al. Science. 2004 Feb 13;303(5660):1010-4. doi: 10.1126/science.1092734. Science. 2004. PMID: 14963330
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD. Kuwana T, et al. Mol Cell. 2005 Feb 18;17(4):525-35. doi: 10.1016/j.molcel.2005.02.003. Mol Cell. 2005. PMID: 15721256
The role of caspase-2 in stress-induced apoptosis.
Bouchier-Hayes L. Bouchier-Hayes L. J Cell Mol Med. 2010 Jun;14(6A):1212-24. doi: 10.1111/j.1582-4934.2010.01037.x. Epub 2010 Feb 16. J Cell Mol Med. 2010. PMID: 20158568 Free PMC article. Review.
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